[HTML][HTML] EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks

SL Banerjee, F Lessard, FJM Chartier, K Jacquet… - Cell Reports, 2022 - cell.com
EPH receptors (EPHRs) constitute the largest family among receptor tyrosine kinases in
humans. They are mainly involved in short-range cell-cell communication events that …

Homotypic receptor-receptor interactions regulating Eph signaling

DB Nikolov, K Xu, JP Himanen - Cell adhesion & migration, 2014 - Taylor & Francis
The Eph receptor tyrosine kinases and their ephrin ligands direct axon pathfinding and
neuronal cell migration, and mediate many other cell-cell communication events. The Ephs …

Architecture of Eph receptor clusters

JP Himanen, L Yermekbayeva… - Proceedings of the …, 2010 - National Acad Sciences
Eph receptor tyrosine kinases and their ephrin ligands regulate cell navigation during
normal and oncogenic development. Signaling of Ephs is initiated in a multistep process …

Recruitment of Eph receptors into signaling clusters does not require ephrin contact

SH Wimmer-Kleikamp, PW Janes, A Squire… - The Journal of cell …, 2004 - rupress.org
Eph receptors and their cell membrane–bound ephrin ligands regulate cell positioning and
thereby establish or stabilize patterns of cellular organization. Although it is recognized that …

Eph/ephrin recognition and the role of Eph/ephrin clusters in signaling initiation

DB Nikolov, K Xu, JP Himanen - … et Biophysica Acta (BBA)-Proteins and …, 2013 - Elsevier
The Eph receptors and their ephrin ligands play crucial roles in a large number of cell–cell
interaction events, including those associated with axon pathfinding, neuronal cell migration …

Eph signaling: a structural view

JP Himanen, DB Nikolov - Trends in neurosciences, 2003 - cell.com
Eph receptors, the largest subfamily of receptor tyrosine kinases, and their ephrin ligands
are important mediators of cell–cell communication regulating cell attachment, shape and …

Eph'ective signaling: forward, reverse and crosstalk

KK Murai, EB Pasquale - Journal of cell science, 2003 - journals.biologists.com
The Eph receptors comprise the largest group of receptor tyrosine kinases and are found in
a wide variety of cell types in developing and mature tissues. Their ligands are the ephrins, a …

PTP1B regulates Eph receptor function and trafficking

E Nievergall, PW Janes, C Stegmayer, ME Vail… - Journal of Cell …, 2010 - rupress.org
Eph receptors orchestrate cell positioning during normal and oncogenic development. Their
function is spatially and temporally controlled by protein tyrosine phosphatases (PTPs), but …

Eph/ephrin signaling: genetic, phosphoproteomic, and transcriptomic approaches

JO Bush, P Soriano - Seminars in cell & developmental biology, 2012 - Elsevier
The Eph receptor tyrosine kinases and their ephrin partners compose a large and complex
family of signaling molecules involved in a wide variety of processes in development …

[HTML][HTML] EphB/ephrinB signaling in cell adhesion and migration

I Park, HS Lee - Molecules and cells, 2015 - Elsevier
Eph receptors and their ligands, ephrins, represent the largest group of the receptor tyrosine
kinase (RTK) family, and they mediate numerous developmental processes in a variety of …