[HTML][HTML] Fluvoxamine: a review of its mechanism of action and its role in COVID-19
Fluvoxamine is a well-tolerated, widely available, inexpensive selective serotonin reuptake
inhibitor that has been shown in a small, double-blind, placebo-controlled, randomized …
inhibitor that has been shown in a small, double-blind, placebo-controlled, randomized …
[HTML][HTML] Fluvoxamine for the early treatment of SARS-CoV-2 infection: a review of current evidence
SARS-CoV-2 infection causes COVID-19, which frequently leads to clinical deterioration
and/or long-lasting morbidity. Academic and governmental experts throughout the USA met …
and/or long-lasting morbidity. Academic and governmental experts throughout the USA met …
[HTML][HTML] Fluvoxamine vs placebo and clinical deterioration in outpatients with symptomatic COVID-19: a randomized clinical trial
EJ Lenze, C Mattar, CF Zorumski, A Stevens… - Jama, 2020 - jamanetwork.com
Importance Coronavirus disease 2019 (COVID-19) may lead to serious illness as a result of
an excessive immune response. Fluvoxamine may prevent clinical deterioration by …
an excessive immune response. Fluvoxamine may prevent clinical deterioration by …
[HTML][HTML] Efficacy and safety of selective serotonin reuptake inhibitors in COVID-19 management: a systematic review and meta-analysis
Background The efficacy of selective serotonin reuptake inhibitors (SSRIs) in the treatment
of acute COVID-19 is still under investigation, with conflicting results reported from …
of acute COVID-19 is still under investigation, with conflicting results reported from …
Safety and efficacy of fluvoxamine in COVID‐19 ICU patients: an open label, prospective cohort trial with matched controls
M Calusic, R Marcec, L Luksa, I Jurkovic… - British journal of …, 2022 - Wiley Online Library
Aims Fluvoxamine, a selective serotonin reuptake inhibitor (SSRI) and sigma‐1 receptor
agonist, has so far shown promise in the prevention of COVID‐19 progression as an early …
agonist, has so far shown promise in the prevention of COVID‐19 progression as an early …
[HTML][HTML] Potential Role of the Antidepressants Fluoxetine and Fluvoxamine in the Treatment of COVID-19
Mapping non-canonical cellular pathways affected by approved medications can accelerate
drug repurposing efforts, which are crucial in situations with a global impact such as the …
drug repurposing efforts, which are crucial in situations with a global impact such as the …
[HTML][HTML] Mechanisms of action of fluvoxamine for COVID-19: a historical review
Y Hashimoto, T Suzuki, K Hashimoto - Molecular psychiatry, 2022 - nature.com
The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by the novel severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) accelerates the discovery of …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) accelerates the discovery of …
[HTML][HTML] The serotonin reuptake inhibitor Fluoxetine inhibits SARS-CoV-2 in human lung tissue
M Zimniak, L Kirschner, H Hilpert, N Geiger, O Danov… - Scientific reports, 2021 - nature.com
To circumvent time-consuming clinical trials, testing whether existing drugs are effective
inhibitors of SARS-CoV-2, has led to the discovery of Remdesivir. We decided to follow this …
inhibitors of SARS-CoV-2, has led to the discovery of Remdesivir. We decided to follow this …
Do the selective serotonin reuptake inhibitor antidepressants fluoxetine and fluvoxamine reduce mortality among patients with COVID-19?
N Hoertel - JAMA network open, 2021 - jamanetwork.com
In a large, multicenter, retrospective cohort study of 83 584 patients with laboratory-
confirmed COVID-19 who had an emergency department or urgent care visit or were …
confirmed COVID-19 who had an emergency department or urgent care visit or were …
[HTML][HTML] Fluoxetine as an anti-inflammatory therapy in SARS-CoV-2 infection
Hyperinflammatory response caused by infections such as Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2) increases organ failure, intensive care unit …
Syndrome Coronavirus 2 (SARS-CoV-2) increases organ failure, intensive care unit …