Role of pyroptosis in diabetes and its therapeutic implications

AA Mamun, Y Wu, F Nasrin, A Akter… - Journal of …, 2021 - Taylor & Francis
Pyroptosis is mainly considered as a new pro-inflammatory mediated-programmed cell
death. In addition, pyroptosis is described by gasdermin-induced pore formation on the …

Advances in the relationship between pyroptosis and diabetic neuropathy

J Xu, S Cai, J Zhao, K Xu, H Ji, C Wu… - Frontiers in Cell and …, 2021 - frontiersin.org
Pyroptosis is a novel programmed cell death process that promotes the release of
interleukin-1β (IL-1β) and interleukin-18 (IL-18) by activating inflammasomes and gasdermin …

Role of pyroptosis in diabetic retinopathy and its therapeutic implications

A Al Mamun, AA Mimi, M Zaeem, Y Wu… - European journal of …, 2021 - Elsevier
Pyroptosis has recently been established as a term of programmed-inflammatory cell death.
Pyroptosis is mainly divided into two molecular signaling pathways, including caspase-1 …

Pyroptosis and inflammasomes in diabetic wound healing

X Mu, X Wu, W He, Y Liu, F Wu, X Nie - Frontiers in Endocrinology, 2022 - frontiersin.org
Diabetic wound is one of the complications of diabetes and is not easy to heal. It often
evolves into chronic ulcers, and severe patients will face amputation. Compared with normal …

A new research hot spot: The role of NLRP3 inflammasome activation, a key step in pyroptosis, in diabetes and diabetic complications

ZW Yu, J Zhang, X Li, Y Wang, YH Fu, XY Gao - Life sciences, 2020 - Elsevier
Pyroptosis is a form of cell death mediated by gasdermin D (GSDMD); it is characterised by
NLRP3 inflammasome activation, caspase activation, cell membrane pore formation, and …

Inhibition of the pyroptosis-associated inflammasome pathway: The important potential mechanism of ginsenosides in ameliorating diabetes and its complications

P Liu, Z Zhang, Y Cai, Y Yang, J Yuan… - European Journal of …, 2023 - Elsevier
Diabetes mellitus (DM) and its complications have become an important global public health
issue, affecting human health and negatively impacting life and lifespan. Pyroptosis is a …

Pyroptosis in diabetes and diabetic nephropathy

Z Cao, D Huang, C Tang, Y Lu, S Huang, C Peng… - Clinica Chimica …, 2022 - Elsevier
Pyroptosis is identified as a pro-inflammatory programmed cell death, mediated by
gasdermins (GSDMs) family of proteins accompanied by pro-inflammatory signals release …

Role of pyroptosis in cardiovascular diseases

C Jia, H Chen, J Zhang, K Zhou, Y Zhuge, C Niu… - International …, 2019 - Elsevier
Pyroptosis is a form of programmed necrosis, and is morphologically and mechanistically
unique form of programmed cell death compared to others, such as apoptosis and …

Pyroptosis in diabetic nephropathy

A Al Mamun, AA Mimi, Y Wu, M Zaeem, MA Aziz… - Clinica Chimica …, 2021 - Elsevier
Diabetic nephropathy (DN), a sterile inflammatory disease, is a serious complication of
diabetes mellitus. However, recent evidence indicates that pyroptosis, a new term for pro …

Pyroptosis-related inflammasome pathway: a new therapeutic target for diabetic cardiomyopathy

Z Cai, S Yuan, X Luan, J Feng, L Deng… - Frontiers in …, 2022 - frontiersin.org
Pyroptosis is a highly specific type of inflammatory programmed cell death that is mediated
by Gasdermine (GSDM). It is characterized by inflammasome activation, caspase activation …