Centromeres are the chromosomal domains required to ensure faithful transmission of the
genome during cell division. They have a central role in preventing aneuploidy, by …

This review is part of the Chromosome segregation and Aneuploidy series that focuses on
the importance of chromosome segregation mechanisms in maintaining genome stability …

Centromeres are the elements of chromosomes that assemble the proteinaceous
kinetochore, maintain sister chromatid cohesion, regulate chromosome attachment to the …

Centromeres are the structural and functional foundation for kinetochore formation, spindle
attachment, and chromosome segregation. In this study, we isolated factors required for …

A fundamental challenge for the survival of all organisms is maintaining the integrity of the
genome in all cells. Cells must therefore segregate their replicated genome equally during …

The centromere is the genetic locus required for chromosome segregation. It is the site of
spindle attachment to the chromosomes and is crucial for the transfer of genetic information …

The development of new technologies and experimental techniques is enabling researchers
to see what was once unable to be seen. For example, the centromere was first seen as the …

Chromosome inheritance depends on centromeres, epigenetically specified regions of
chromosomes. While conventional human centromeres are known to be built of long tandem …

Centromeres mediate the faithful segregation of eukaryotic chromosomes. Yet they display a
remarkable range in size and complexity across eukaryotes, from∼ 125 bp in budding yeast …

Centromeres are the eukaryotic chromosomal sites at which the kinetochore forms and
attaches to spindle microtubules to orchestrate chromosomal segregation in mitosis and …