Osteochondral (OC) repair is an extremely challenging topic due to the complex biphasic
structure and poor intrinsic regenerative capability of natural osteochondral tissue. In …

Osteochondral defects are difficult to treat because the articular cartilage and the
subchondral bone have dissimilar characteristics and abilities to regenerate. Bioinspired …

The tissue engineering approach for repairing osteochondral (OC) defects involves the
fabrication of a biological tissue scaffold that mimics the physiological properties of natural …

Osteochondral defects are caused by injury to both the articular cartilage and subchondral
bone within skeletal joints. They can lead to irreversible joint damage and increase the risk …

Repairing osteochondral defect (OCD) using advanced biomaterials that structurally,
biologically, and mechanically fulfill the criteria for stratified tissue regeneration remains a …

Interest in osteochondral repair has been increasing with the growing number of sports-
related injuries, accident traumas, and congenital diseases and disorders. Although …

The management of osteoarthritis (OA) remains challenging and controversial. Although
several clinical options exist for the treatment of OA, regeneration of the damaged articular …

Osteochondral (OC) defects cannot adequately repair themselves due to their sophisticated
layered structure and lack of blood supply in cartilage. Although therapeutic interventions …

Repairing articular osteochondral defects present considerable challenges in self‐repair
due to the complex tissue structure and low proliferation of chondrocytes. Conventional …

Introduction Identification of a suitable treatment for osteochondral repair presents a major
challenge due to existing limitations and an urgent clinical need remains for an off-the-shelf …