[HTML][HTML] Endogenous retroviruses in nervous system disorders

V Gröger, A Emmer, MS Staege, H Cynis - Pharmaceuticals, 2021 - mdpi.com
Human endogenous retroviruses (HERV) have been implicated in the pathogenesis of
several nervous system disorders including multiple sclerosis and amyotrophic lateral …

Human endogenous retroviruses and the nervous system

RN Douville, A Nath - Handbook of clinical neurology, 2014 - Elsevier
Within the human genome reside thousands of retrovirus-like sequences which comprise
nearly 8% of the human genome. Originating from ancient retroviruses that overcame host …

[HTML][HTML] Human endogenous retroviruses in neurological diseases

P Küry, A Nath, A Créange, A Dolei, P Marche… - Trends in molecular …, 2018 - cell.com
The causes of multiple sclerosis and amyotrophic lateral sclerosis have long remained
elusive. A new category of pathogenic components, normally dormant within human …

Human endogenous retroviruses in the aetiology of MS

T Christensen - Acta Neurologica Scandinavica, 2017 - Wiley Online Library
Several lines of investigation have provided strong indications for an association between
the immune‐mediated, neurologic disease multiple sclerosis (MS) and human endogenous …

Human endogenous retroviruses in neurologic disease

T Christensen - Apmis, 2016 - Wiley Online Library
Endogenous retroviruses are pathogenic–in other species than the human. Disease
associations for Human Endogenous RetroViruses (HERV s) are emerging, but so far an …

[HTML][HTML] Human endogenous retroviruses and multiple sclerosis: innocent bystanders or disease determinants?

JM Antony, AM DesLauriers, RK Bhat… - … et Biophysica Acta (BBA …, 2011 - Elsevier
Human endogenous retroviruses (HERVs) constitute 5–8% of human genomic DNA and are
replication incompetent despite expression of individual HERV genes from different …

Human endogenous retrovirus-K contributes to motor neuron disease

W Li, MH Lee, L Henderson, R Tyagi… - Science translational …, 2015 - science.org
The role of human endogenous retroviruses (HERVs) in disease pathogenesis is unclear.
We show that HERV-K is activated in a subpopulation of patients with sporadic amyotrophic …

[HTML][HTML] Neural cell responses upon exposure to human endogenous retroviruses

J Gruchot, D Kremer, P Küry - Frontiers in genetics, 2019 - frontiersin.org
Human endogenous retroviruses (HERVs) are ancient retroviral elements, which invaded
the human germ line several million years ago. Subsequent retrotransposition events …

[HTML][HTML] Endogenous retroviruses activity as a molecular signature of neurodevelopmental disorders

E Balestrieri, C Matteucci, C Cipriani, S Grelli… - International Journal of …, 2019 - mdpi.com
Human endogenous retroviruses (HERVs) are genetic elements resulting from relics of
ancestral infection of germline cells, now recognized as cofactors in the etiology of several …

Association of human endogenous retroviruses with multiple sclerosis and possible interactions with herpes viruses

T Christensen - Reviews in medical virology, 2005 - Wiley Online Library
The hypothesis that human endogenous retroviruses (HERVs) play a role in autoimmune
diseases is subject to increasing attention. HERVs represent both putative susceptibility …