Phosphatidic acid: from pleiotropic functions to neuronal pathology
Among the cellular lipids, phosphatidic acid (PA) is a peculiar one as it is at the same time a
key building block of phospholipid synthesis and a major lipid second messenger conveying …
key building block of phospholipid synthesis and a major lipid second messenger conveying …
Phosphatidic acid–a simple phospholipid with multiple faces
J Zegarlinska, M Piaścik, AF Sikorski… - Acta Biochimica …, 2018 - abp.ptbioch.edu.pl
Phosphatidic acid (PA) is the simplest glycerophospholipid naturally occurring in living
organisms, and even though its content among other cellular lipids is minor, it is drawing …
organisms, and even though its content among other cellular lipids is minor, it is drawing …
Phosphatidic acid in neuronal development: a node for membrane and cytoskeleton rearrangements
Phosphatidic acid (PA) is the simplest phospholipid naturally existing in all-living organisms.
It constitutes only a minor fraction of the total cell lipids but has attracted considerable …
It constitutes only a minor fraction of the total cell lipids but has attracted considerable …
Regulation of membrane turnover by phosphatidic acid: cellular functions and disease implications
Phosphatidic acid (PA) is a simple glycerophospholipid with a well-established role as an
intermediate in phospholipid biosynthesis. In addition to its role in lipid biosynthesis, PA has …
intermediate in phospholipid biosynthesis. In addition to its role in lipid biosynthesis, PA has …
Phosphatidic acid: an emerging versatile class of cellular mediators
SC Kim, X Wang - Essays in Biochemistry, 2020 - portlandpress.com
Lipids function not only as the major structural components of cell membranes, but also as
molecular messengers that transduce signals to trigger downstream signaling events in the …
molecular messengers that transduce signals to trigger downstream signaling events in the …
Phosphatidic acid: From biophysical properties to diverse functions
Phosphatidic acid (PA), the simplest phospholipid, acts as a key metabolic intermediate and
second messenger that impacts diverse cellular and physiological processes across species …
second messenger that impacts diverse cellular and physiological processes across species …
Phosphatidic acid-mediated signaling
Phosphatidic acid (PA) is recognized as an important class of lipid messengers. The cellular
PA levels are dynamic; PA is produced and metabolized by several enzymatic reactions …
PA levels are dynamic; PA is produced and metabolized by several enzymatic reactions …
Putting the pH into phosphatidic acid signaling
JJH Shin, CJR Loewen - BMC biology, 2011 - Springer
The lipid phosphatidic acid (PA) has important roles in cell signaling and metabolic
regulation in all organisms. New evidence indicates that PA also has an unprecedented role …
regulation in all organisms. New evidence indicates that PA also has an unprecedented role …
Messenger functions of phosphatidic acid
D English, Y Cui, RA Siddiqui - Chemistry and physics of lipids, 1996 - Elsevier
Under physiological conditions, phosphatidic acid (PA) is an anionic phospholipid with
moderate biological reactivity. Some of its biological effects can be attributed to lyso-PA and …
moderate biological reactivity. Some of its biological effects can be attributed to lyso-PA and …
Biological effects of lysophosphatidic acid in the nervous system
F Frisca, RA Sabbadini, Y Goldshmit… - International review of cell …, 2012 - Elsevier
Lysophosphatidic acid (LPA) is a bioactive lipid that regulates a broad range of cellular
effects in various cell types, leading to a variety of responses in tissues, including in the …
effects in various cell types, leading to a variety of responses in tissues, including in the …
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