Clinicopathological and molecular correlations in traditional serrated adenoma
S Sekine, S Yamashita, M Yamada… - Journal of …, 2020 - Springer
Background Traditional serrated adenoma (TSA) is the least common type of colorectal
serrated polyp, which exhibits considerable morphological and molecular diversity. Methods …
serrated polyp, which exhibits considerable morphological and molecular diversity. Methods …
Traditional serrated adenoma: an overview of pathology and emphasis on molecular pathogenesis
Objective To provide an overview of the pathology and molecular pathogenesis of traditional
serrated adenomas (TSA). Design Describe the morphology and molecules that play a role …
serrated adenomas (TSA). Design Describe the morphology and molecules that play a role …
Traditional serrated adenoma has two distinct genetic pathways for molecular tumorigenesis with potential neoplastic progression
Y Tanaka, M Eizuka, N Uesugi, K Kawasaki… - Journal of …, 2020 - Springer
Background Recent studies have shown that traditional serrated adenoma (TSA) can be
classified into BRAF and KRAS subtypes. Here, we examined the clinicopathological and …
classified into BRAF and KRAS subtypes. Here, we examined the clinicopathological and …
[HTML][HTML] Molecular biomarkers of sessile serrated adenoma/polyps
P Kanth, KE Boylan, MP Bronner… - Clinical and …, 2019 - journals.lww.com
OBJECTIVES: Sessile serrated adenoma/polyps (SSA/Ps) contribute up to 30% of all colon
cancers. There is considerable histological overlap between SSA/Ps and hyperplastic …
cancers. There is considerable histological overlap between SSA/Ps and hyperplastic …
Frequent PTPRK–RSPO3 fusions and RNF43 mutations in colorectal traditional serrated adenoma
S Sekine, S Yamashita, T Tanabe… - The Journal of …, 2016 - Wiley Online Library
The molecular mechanisms underlying the serrated pathway of colorectal tumourigenesis,
particularly those related to traditional serrated adenomas (TSAs), are still poorly …
particularly those related to traditional serrated adenomas (TSAs), are still poorly …
Acquisition of WNT pathway gene alterations coincides with the transition from precursor polyps to traditional serrated adenomas
T Hashimoto, R Ogawa, H Yoshida… - The American journal …, 2019 - journals.lww.com
Colorectal traditional serrated adenomas (TSAs) are often associated with precursor polyps,
including hyperplastic polyps and sessile serrated adenoma/polyps. To elucidate the …
including hyperplastic polyps and sessile serrated adenoma/polyps. To elucidate the …
[HTML][HTML] Superficially serrated adenoma: a proposal for a novel subtype of colorectal serrated lesion
T Hashimoto, Y Tanaka, R Ogawa, T Mori, H Yoshida… - Modern Pathology, 2018 - Elsevier
We describe a series of colorectal polyps characterized by mixed adenomatous and
serrated features, herein referred to as superficially serrated adenomas. Twenty superficially …
serrated features, herein referred to as superficially serrated adenomas. Twenty superficially …
[HTML][HTML] A clinicopathological and molecular analysis of 200 traditional serrated adenomas
The traditional serrated adenoma is the least common colorectal serrated polyp. The
clinicopathological features and molecular drivers of these polyps require further …
clinicopathological features and molecular drivers of these polyps require further …
Clinicopathologic and genetic characterization of traditional serrated adenomas of the colon
Traditional serrated adenomas (TSAs) are a type of colorectal polyp with neoplastic
potential. Immunohistochemical analysis and sequencing were performed on 24 TSAs from …
potential. Immunohistochemical analysis and sequencing were performed on 24 TSAs from …
Prevalence and molecular characterisation of the sessile serrated adenoma in a subset of the Chinese population
Y Qiu, X Fu, W Zhang, Y Xu, L Xiao, X Chen… - Journal of clinical …, 2014 - jcp.bmj.com
Aims The incidence and mortality rates from right-sided colorectal cancers (CRCs) have not
decreased in recent years. It is very likely that a significant proportion of these cancers …
decreased in recent years. It is very likely that a significant proportion of these cancers …