Glioblastoma (GBM) is the most aggressive primary brain tumor with poor prognosis and
high recurrence rate. The presence of the blood–brain barrier (BBB) prevents diagnostic and …

Gliomas are the most common primary brain tumors in adults, accounting for 80% of primary
intracranial tumors. Due to the heterogeneous and infiltrating nature of malignant gliomas …

Malignant glioma remains incurable largely due to the aggressive and infiltrative nature, as
well as the existence of blood–brain-barrier (BBB). Precise diagnosis of glioma, which aims …

The difficulty in delineating the glioma margins in brain is a major obstacle for its completed
resection, which leads to the disproportionately high recurrence and mortality. Besides the …

Gadolinium (Gd) chelate contrast-enhanced magnetic resonance imaging (MRI) is a
preferred method of glioma detection and preoperative localisation because it offers high …

Nowadays, a malignant brain tumor is one of the most life-threatening diseases with poor
prognosis, high risk of recurrence, and low survival rate for patients because of the existence …

Precise imaging is essential for the accurate diagnosis and surgical guidance of brain
diseases but it is challenging due to the difficulties in crossing the blood-brain barrier (BBB) …

Glioblastoma (GBM), a highly malignant glioma of the central nervous system, is the most
dread and common brain tumor with a high rate of therapeutic resistance and recurrence …

Glioma is often referred to as one of the most dreadful central nervous system (CNS)-specific
tumors with rapidly-proliferating cancerous glial cells, accounting for nearly half of the brain …

Malignant tumors have been one of the major reasons for deaths worldwide. Timely and
accurate diagnosis as well as effective intervention of tumors play an essential role in the …