Background The gut microbiota contributes to macrophage-mediated inflammation in
adipose tissue with consumption of an obesogenic diet, thus driving the development of …

Scope Two hydrogenated xanthohumol (XN) derivatives, α, β‐dihydro‐XN (DXN) and
tetrahydro‐XN (TXN), improved parameters of metabolic syndrome (MetS), a critical risk …

Monosodium glutamate (MSG)-induced abdominal obesity, conventionally caused by
hypothalamic damage, is a critical risk factor for health problem. Microbiota-gut-brain axis …

Background & Aims While it is widely accepted that obesity is associated with low-grade
systemic inflammation, the molecular origin of the inflammation remains unknown. Here, we …

Scope The polyphenol xanthohumol (XN) improves dysfunctional glucose and lipid
metabolism in diet‐induced obesity animal models. Because XN changes intestinal …

Resveratrol (RSV) is a natural polyphenol with anti-obesity effects. However, the
mechanisms of anti-obesity remain unclear due to its low bioavailability. Recent evidence …

Xanthohumol (XN), a polyphenol found in the hop plant (Humulus lupulus), has antioxidant,
anti-inflammatory, prebiotic, and anti-hyperlipidemic activity. Preclinical evidence suggests …

Metabolic syndrome (MS) is a common metabolic disorder characterized by obesity, insulin
resistance, cardiovascular disease and gut microbiota dysbiosis. Pu-erh tea and its …

Background & Aims Consumption of a low-fiber, high-fat, Western-style diet (WSD) induces
adiposity and adipose inflammation characterized by increases in the M1: M2 macrophage …

Aberrations in gut microbiota are associated with metabolic disorders, including obesity.
However, whether shifts in the microbiota profile during obesity are a characteristic of the …