[HTML][HTML] An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples
A Ahouidi, M Ali, J Almagro-Garcia… - Wellcome Open …, 2021 - ncbi.nlm.nih.gov
A major obstacle to malaria elimination is the great capacity of the parasite and vector
populations to evolve in response to malaria control interventions. The widespread use of …
populations to evolve in response to malaria control interventions. The widespread use of …
[HTML][HTML] Pf7: an open dataset of Plasmodium falciparum genome variation in 20,000 worldwide samples
MMA Hamid, MH Abdelraheem… - Wellcome open …, 2023 - ncbi.nlm.nih.gov
Abstract We describe the MalariaGEN Pf7 data resource, the seventh release of
Plasmodium falciparum genome variation data from the MalariaGEN network. It comprises …
Plasmodium falciparum genome variation data from the MalariaGEN network. It comprises …
Genome variation and evolution of the malaria parasite Plasmodium falciparum
Infections with the malaria parasite Plasmodium falciparum result in more than 1 million
deaths each year worldwide. Deciphering the evolutionary history and genetic variation of P …
deaths each year worldwide. Deciphering the evolutionary history and genetic variation of P …
Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum
The malaria parasite Plasmodium falciparum has a great capacity for evolutionary
adaptation to evade host immunity and develop drug resistance. Current understanding of …
adaptation to evade host immunity and develop drug resistance. Current understanding of …
[HTML][HTML] Harnessing genomics and genome biology to understand malaria biology
SK Volkman, DE Neafsey, SF Schaffner… - Nature Reviews …, 2012 - nature.com
Malaria is an important human disease and is the target of a global eradication campaign.
New technological and informatics advancements in population genomics are being …
New technological and informatics advancements in population genomics are being …
[HTML][HTML] Genetic diversity and drug resistance surveillance of Plasmodium falciparum for malaria elimination: is there an ideal tool for resource-limited sub-Saharan …
TO Apinjoh, A Ouattara, VPK Titanji, A Djimde… - Malaria journal, 2019 - Springer
The intensification of malaria control interventions has resulted in its global decline, but it
remains a significant public health burden especially in sub-Saharan Africa (sSA) …
remains a significant public health burden especially in sub-Saharan Africa (sSA) …
Describing the current status of Plasmodium falciparum population structure and drug resistance within mainland Tanzania using molecular inversion probes
KA Moser, RA Madebe, O Aydemir… - Molecular …, 2021 - Wiley Online Library
High‐throughput Plasmodium genomic data is increasingly useful in assessing prevalence
of clinically important mutations and malaria transmission patterns. Understanding parasite …
of clinically important mutations and malaria transmission patterns. Understanding parasite …
A genome-wide map of diversity in Plasmodium falciparum
SK Volkman, PC Sabeti, D DeCaprio, DE Neafsey… - Nature …, 2007 - nature.com
Genetic variation allows the malaria parasite Plasmodium falciparum to overcome
chemotherapeutic agents, vaccines and vector control strategies and remain a leading …
chemotherapeutic agents, vaccines and vector control strategies and remain a leading …
[HTML][HTML] Genome-wide SNP genotyping highlights the role of natural selection in Plasmodium falciparumpopulation divergence
Abstract Background The malaria parasite Plasmodium falciparum exhibits abundant
genetic diversity, and this diversity is key to its success as a pathogen. Previous efforts to …
genetic diversity, and this diversity is key to its success as a pathogen. Previous efforts to …
[HTML][HTML] Advances and opportunities in malaria population genomics
Almost 20 years have passed since the first reference genome assemblies were published
for Plasmodium falciparum, the deadliest malaria parasite, and Anopheles gambiae, the …
for Plasmodium falciparum, the deadliest malaria parasite, and Anopheles gambiae, the …