[HTML][HTML] An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

A Ahouidi, M Ali, J Almagro-Garcia… - Wellcome Open …, 2021 - ncbi.nlm.nih.gov
A major obstacle to malaria elimination is the great capacity of the parasite and vector
populations to evolve in response to malaria control interventions. The widespread use of …

[HTML][HTML] Pf7: an open dataset of Plasmodium falciparum genome variation in 20,000 worldwide samples

MMA Hamid, MH Abdelraheem… - Wellcome open …, 2023 - ncbi.nlm.nih.gov
Abstract We describe the MalariaGEN Pf7 data resource, the seventh release of
Plasmodium falciparum genome variation data from the MalariaGEN network. It comprises …

Genome variation and evolution of the malaria parasite Plasmodium falciparum

DC Jeffares, A Pain, A Berry, AV Cox, J Stalker… - Nature …, 2007 - nature.com
Infections with the malaria parasite Plasmodium falciparum result in more than 1 million
deaths each year worldwide. Deciphering the evolutionary history and genetic variation of P …

Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum

A Miles, Z Iqbal, P Vauterin, R Pearson… - Genome …, 2016 - genome.cshlp.org
The malaria parasite Plasmodium falciparum has a great capacity for evolutionary
adaptation to evade host immunity and develop drug resistance. Current understanding of …

[HTML][HTML] Harnessing genomics and genome biology to understand malaria biology

SK Volkman, DE Neafsey, SF Schaffner… - Nature Reviews …, 2012 - nature.com
Malaria is an important human disease and is the target of a global eradication campaign.
New technological and informatics advancements in population genomics are being …

[HTML][HTML] Genetic diversity and drug resistance surveillance of Plasmodium falciparum for malaria elimination: is there an ideal tool for resource-limited sub-Saharan …

TO Apinjoh, A Ouattara, VPK Titanji, A Djimde… - Malaria journal, 2019 - Springer
The intensification of malaria control interventions has resulted in its global decline, but it
remains a significant public health burden especially in sub-Saharan Africa (sSA) …

Describing the current status of Plasmodium falciparum population structure and drug resistance within mainland Tanzania using molecular inversion probes

KA Moser, RA Madebe, O Aydemir… - Molecular …, 2021 - Wiley Online Library
High‐throughput Plasmodium genomic data is increasingly useful in assessing prevalence
of clinically important mutations and malaria transmission patterns. Understanding parasite …

A genome-wide map of diversity in Plasmodium falciparum

SK Volkman, PC Sabeti, D DeCaprio, DE Neafsey… - Nature …, 2007 - nature.com
Genetic variation allows the malaria parasite Plasmodium falciparum to overcome
chemotherapeutic agents, vaccines and vector control strategies and remain a leading …

[HTML][HTML] Genome-wide SNP genotyping highlights the role of natural selection in Plasmodium falciparumpopulation divergence

DE Neafsey, SF Schaffner, SK Volkman, D Park… - Genome biology, 2008 - Springer
Abstract Background The malaria parasite Plasmodium falciparum exhibits abundant
genetic diversity, and this diversity is key to its success as a pathogen. Previous efforts to …

[HTML][HTML] Advances and opportunities in malaria population genomics

DE Neafsey, AR Taylor, BL MacInnis - Nature Reviews Genetics, 2021 - nature.com
Almost 20 years have passed since the first reference genome assemblies were published
for Plasmodium falciparum, the deadliest malaria parasite, and Anopheles gambiae, the …