Regulation of alternative sigma factor use

S Österberg, T Peso-Santos… - Annual review of …, 2011 - annualreviews.org
Alternative bacterial sigma factors bind the catalytic core RNA polymerase to confer
promoter selectivity on the holoenzyme. The different holoenzymes are thus programmed to …

The molecular basis of selective promoter activation by the σS subunit of RNA polymerase

A Typas, G Becker, R Hengge - Molecular microbiology, 2007 - Wiley Online Library
Different environmental stimuli cause bacteria to exchange the sigma subunit in the RNA
polymerase (RNAP) and, thereby, tune their gene expression according to the newly …

Bacterial sigma factors and anti-sigma factors: structure, function and distribution

MS Paget - Biomolecules, 2015 - mdpi.com
Sigma factors are multi-domain subunits of bacterial RNA polymerase (RNAP) that play
critical roles in transcription initiation, including the recognition and opening of promoters as …

Where to begin? Sigma factors and the selectivity of transcription initiation in bacteria

JD Helmann - Molecular microbiology, 2019 - Wiley Online Library
Transcription is the fundamental process that enables the expression of genetic information.
DNA‐directed RNA polymerase (RNAP) uses one strand of the DNA duplex as template to …

Signal sensory systems that impact σ54-dependent transcription

V Shingler - FEMS microbiology reviews, 2011 - academic.oup.com
Alternative σ-factors of bacteria bind core RNA polymerase to program the specific promoter
selectivity of the holoenzyme. Signal-responsive changes in the availability of different σ …

Bacterial sigma factors: a historical, structural, and genomic perspective

A Feklístov, BD Sharon, SA Darst… - Annual review of …, 2014 - annualreviews.org
Transcription initiation is the crucial focal point of gene expression in prokaryotes. The key
players in this process, sigma factors (σs), associate with the catalytic core RNA polymerase …

Modus operandi of the bacterial RNA polymerase containing the σ54 promoter‐specificity factor

S Wigneshweraraj, D Bose, PC Burrows… - Molecular …, 2008 - Wiley Online Library
Bacterial sigma (σ) factors confer gene specificity upon the RNA polymerase, the central
enzyme that catalyses gene transcription. The binding of the alternative σ factor σ54 confers …

The essential activities of the bacterial sigma factor

MC Davis, CA Kesthely, EA Franklin… - Canadian journal of …, 2017 - cdnsciencepub.com
Transcription is the first and most heavily regulated step in gene expression. Sigma (σ)
factors are general transcription factors that reversibly bind RNA polymerase (RNAP) and …

Stationary phase reorganisation of the Escherichia coli transcription machinery by Crl protein, a fine‐tuner of σs activity and levels

A Typas, C Barembruch, A Possling, R Hengge - The EMBO journal, 2007 - embopress.org
Upon environmental changes, bacteria reschedule gene expression by directing alternative
sigma factors to core RNA polymerase (RNAP). This sigma factor switch is achieved by …

Interaction of Bacillus subtilis extracytoplasmic function (ECF) sigma factors with the N-terminal regions of their potential anti-sigma factors

M Yoshimura, K Asai, Y Sadaie… - Microbiology, 2004 - microbiologyresearch.org
Extracytoplasmic function (ECF) sigma factors constitute a diverse family of proteins, within
the class of the sigma 70 subunit of RNA polymerase. Most members of the family studied to …