Serotonin receptors

DE Nichols, CD Nichols - Chemical reviews, 2008 - ACS Publications
Serotonin, 5-hydroxytryptamine (5-HT), is one of the class of monoamine neurontransmitters,
all of which have a chemical template comprised of a basic amino group separated from an …

Higher-End Serotonin Receptors:  5-HT5, 5-HT6, and 5-HT7

RA Glennon - Journal of medicinal chemistry, 2003 - ACS Publications
Serotonin (5-hydroxytryptamine, 5-HT; 1) is a major neurotransmitter that is believed to
produce many of its effects via interaction at seven populations of 5-HT receptors, 5-HT1 to 5 …

[图书][B] The serotonin receptors: from molecular pharmacology to human therapeutics

BL Roth - 2008 - books.google.com
A comprehensive, state-of-the-art review of our current understanding of the molecular and
structural biology of 5-HT receptors and their potential use for drug discovery. The authors …

[PDF][PDF] Serotonin receptors-from molecular biology to clinical applications

M Pytliak, V Vargová, V Mechírová… - Physiological …, 2011 - researchgate.net
Serotonin Receptors – From Molecular Biology to Clinical Applications Page 1
PHYSIOLOGICAL RESEARCH • ISSN 0862-8408(print) • ISSN 1802-9973(online) © 2011 …

Molecular, pharmacological and functional diversity of 5-HT receptors

D Hoyer, JP Hannon, GR Martin - Pharmacology Biochemistry and …, 2002 - Elsevier
Serotonin (5-hydroxytryptamine, 5-HT) is probably unique among the monoamines in that its
effects are subserved by as many as 13 distinct heptahelical, G-protein-coupled receptors …

Molecular biology of serotonin receptors-structure and function at the molecular level

WK Kroeze, K Kristiansen… - Current topics in medicinal …, 2002 - ingentaconnect.com
5-hydroxytryptamine (5-HT serotonin) is a neurotransmitter essential for a large number of
physiological processes including the regulation of vascular and non-vascular smooth …

Structural basis for molecular recognition at serotonin receptors

C Wang, Y Jiang, J Ma, H Wu, D Wacker, V Katritch… - Science, 2013 - science.org
Serotonin or 5-hydroxytryptamine (5-HT) regulates a wide spectrum of human physiology
through the 5-HT receptor family. We report the crystal structures of the human 5-HT1B G …

Characterization of the novel human serotonin receptor subunits 5-HT3C, 5-HT3D, and 5-HT3E

B Niesler, J Walstab, S Combrink, D Möller… - Molecular …, 2007 - ASPET
Within the family of serotonin receptors, the 5-hydroxytryptamine-3 (5-HT3) receptor is the
only ligand-gated ion channel. It is composed of five subunits, of which the 5-HT3A and 5 …

Selective serotonin reuptake inhibitors pathway

K Sangkuhl, TE Klein, RB Altman - Pharmacogenetics and …, 2009 - journals.lww.com
Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter that influences multiple
processes, including autonomic function, motor activity, hormone secretion, cognition, and …

The serotonin 5-HT7 receptors: two decades of research

E Gellynck, K Heyninck, KW Andressen… - Experimental brain …, 2013 - Springer
Like most neurotransmitters, serotonin possesses a simple structure. However, the
pharmacological consequences are more complex and diverse. Serotonin is involved in …