Carcinogenetic impact of ADH1B and ALDH2 genes on squamous cell carcinoma risk of the esophagus with regard to the consumption of alcohol, tobacco and betel …

CH Lee, JM Lee, DC Wu, YG Goan… - … journal of cancer, 2008 - Wiley Online Library
The consumption of alcohol, tobacco and betel quid has been found to be an important
contributor to esophageal squamous cell carcinoma (ESCC) in Taiwan. The genotoxic effect …

Relationship between esophageal squamous cell carcinoma risk and alcohol‐related ALDH2 and ADH1B polymorphisms: Evidence from a meta‐analysis and …

B Zhang, YH Peng, Y Luo, CQ Hong, YW Lin… - Cancer …, 2023 - Wiley Online Library
Background Previous studies have shown that ALDH2 and ADH1B genes may be
associated with alcohol metabolism and the risk of esophageal squamous cell carcinoma …

Interactive effects of lifetime alcohol consumption and alcohol and aldehyde dehydrogenase polymorphisms on esophageal cancer risks

YJ Chen, C Chen, DC Wu, CH Lee… - … journal of cancer, 2006 - Wiley Online Library
In our previous study, we found that polymorphisms of alcohol and aldehyde
dehydrogenase (ADH1B and ALDH2) are important risks for esophageal squamous cell …

Strong interaction between the effects of alcohol consumption and smoking on oesophageal squamous cell carcinoma among individuals with ADH1B and/or ALDH2 …

F Tanaka, K Yamamoto, S Suzuki, H Inoue… - Gut, 2010 - gut.bmj.com
Background Oesophageal squamous cell carcinoma (OSCC) is considered a difficult cancer
to cure. The detection of environmental and genetic factors is important for prevention on an …

Single nucleotide polymorphisms of ADH1B, ADH1C and ALDH2 genes and esophageal cancer: A population‐based case–control study in China

M Wu, SC Chang, E Kampman, J Yang… - … journal of cancer, 2013 - Wiley Online Library
Alcohol drinking is a major risk factor for esophageal cancer (EC) and the metabolism of
ethanol has been suggested to play an important role in esophageal carcinogenesis …

Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk

RI Cui, Y Kamatani, A Takahashi, M Usami, N Hosono… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: Esophageal squamous cell carcinoma (ESCC) is prevalent among
Asian populations, with marked regional variations in incidence and mortality. Patients with …

[HTML][HTML] Relationship between genetic polymorphisms of ALDH2 and ADH1B and esophageal cancer risk: a meta-analysis

SJ Yang, A Yokoyama, T Yokoyama… - World journal of …, 2010 - ncbi.nlm.nih.gov
AIM: To evaluate the contribution of alcohol dehydrogenase-1B (ADH1B) and aldehyde
dehydrogenase-2 (ALDH2) polymorphisms to the risk of esophageal cancer. METHODS …

Lifestyle habits and genetic susceptibility and the risk of esophageal cancer in the Thai population

P Boonyaphiphat, P Thongsuksai, H Sriplung… - Cancer letters, 2002 - Elsevier
The association of lifestyle habits and polymorphism of ADH2 and ALDH2 genes with the
risk of esophageal cancer in Thai population was investigated in a hospital-based case …

Genetic modulation of ADH1B and ALDH2 polymorphisms with regard to alcohol and tobacco consumption for younger aged esophageal squamous cell carcinoma …

CH Lee, DC Wu, IC Wu, YG Goan… - … journal of cancer, 2009 - Wiley Online Library
Genetic variants in alcohol dehydrogenase‐1B (ADH1B) and aldehyde dehydrogenase‐2
(ALDH2) genes modulate acetaldehyde removal upon alcohol ingestion. Although these …

Genetic polymorphisms of alcohol and aldehyde dehydrogenases and glutathione S -transferase M1 and drinking, smoking, and diet in Japanese men …

A Yokoyama, H Kato, T Yokoyama, T Tsujinaka… - …, 2002 - academic.oup.com
The genetic polymorphisms of aldehyde dehydrogenase-2 (ALDH2), alcohol
dehydrogenase-2 (ADH2), ADH3, and glutathione S-transferase M1 (GSTM1) influence the …