Genome-wide association studies (GWAS) aim to identify common genetic variants that are
associated with traits and diseases. Since 2005, more than 5,000 GWAS have been …

The past few years have seen significant advances in the identification of genetic factors that
contribute to complex disease. Progress in cardiovascular diseases (CVD) has been …

The spring of 2012 marked the fifth anniversary of the widespread appearance in the
biomedical literature of genome-wide association studies (GWAS) of diseases of adulthood …

Background—Genome-wide association (GWA) platforms have yielded a rapidly increasing
number of new genetic markers. The ability of these markers to improve prediction of …

As investigators plan the next round of genome-wide association studies (GWAS), cohorts of
more than 100 000 individuals are being proposed as the solution to the “missing …

Genome-wide association studies (GWAS) have identified several genetic variants
associated with coronary heart disease (CHD), and variations in plasma lipoproteins and …

BACKGROUND Genomewide association studies have led to an enormous boost in the
identification of susceptibility genes for cardiovascular diseases. This review aims to …

Background Traditional genome-wide association studies are generally limited in their
ability explain a large portion of genetic risk for most common diseases. We sought to use …

Cardiovascular diseases are leading causes for death worldwide. Genetic disposition jointly
with traditional risk factors precipitates their manifestation. Whereas the implications of a …

Human genetics is a powerful tool for discovering causal mediators of human disease and
physiology. Cardiovascular diseases with late onset in the lifecourse have historically not …