Molecular pathology of thyroid tumours of follicular cells: a review of genetic alterations and their clinicopathological relevance

G Acquaviva, M Visani, A Repaci, KJ Rhoden… - …, 2018 - Wiley Online Library
Thyroid cancer is the most common endocrine malignancy. Knowledge of the molecular
pathology of thyroid tumours originating from follicular cells has greatly advanced in the past …

Molecular genetics of follicular-derived thyroid cancer

E Macerola, AM Poma, P Vignali, A Basolo, C Ugolini… - Cancers, 2021 - mdpi.com
Simple Summary Thyroid tumors that derive from follicular cells are not a homogeneous
entity, showing variable morphological appearance and different degrees of differentiation …

Perspective: lessons learned from molecular genetic studies of thyroid cancer—insights into pathogenesis and tumor-specific therapeutic targets

JA Fagin - Endocrinology, 2002 - academic.oup.com
Thyroid cancer derived from follicular cells is the most common endocrine malignancy. The
past decade has seen progress in our understanding of the pathogenesis of the various …

Molecular events in follicular thyroid tumors

TG Kroll - Molecular basis of thyroid cancer, 2004 - Springer
The analyses of human thyroid tumor tissues have proven informative in identifying key
molecular events in epithelial neoplasia. The thyroid gland gives rise to a variety of epithelial …

Cytogenetics and molecular genetics of carcinomas arising from thyroid epithelial follicular cells

MA Pierotti, I Bongarzone, MG Borrello… - Genes …, 1996 - Wiley Online Library
Cytogenetic and molecular analyses of thyroid tumors have indicated that these neoplasms
represent a good model for analyzing human epithelial cell multistep carcinogenesis. They …

[PDF][PDF] Classification and general considerations of thyroid cancer

H Katoh, K Yamashita, T Enomoto, M Watanabe - Ann Clin Pathol, 2015 - academia.edu
Thyroid cancer is the most common malignancy in endocrine system, composed of four
major types; papillary thyroid carcinoma, follicular thyroid carcinoma, anaplastic thyroid …

Molecular Pathology of Non-familial Follicular Epithelial–Derived Thyroid Cancer in Adults: From RAS/BRAF-like Tumor Designations to Molecular Risk Stratification

P Soares, AA Povoa, M Melo, J Vinagre, V Maximo… - Endocrine …, 2021 - Springer
This review addresses the impact of molecular alterations on the diagnosis and prognosis of
differentiated thyroid carcinoma (DTC), including papillary, follicular, and well-differentiated …

How molecular pathology is changing and will change the therapeutics of patients with follicular cell-derived thyroid cancer

JP Couto, H Prazeres, P Castro, J Lima… - Journal of clinical …, 2009 - jcp.bmj.com
Well-differentiated thyroid carcinomas comprise two well-defined histological types: papillary
and follicular (PTCs and FTCs, respectively). Despite being derived from the same cell …

Molecular markers for discrimination of benign and malignant follicular thyroid tumors

M Fryknäs, U Wickenberg-Bolin, H Göransson… - Tumor Biology, 2006 - karger.com
Objective: To identify molecular markers useful for the diagnostic discrimination of benign
and malignant follicular thyroid tumors. Methods: A panel of thyroid tumors was …

ENDOCRINE TUMOURS: Genetic predictors of thyroid cancer outcome

C Tavares, M Melo… - European journal of …, 2016 - academic.oup.com
Genetic predictors of outcome are reviewed in the context of a disease–cancer–that can be
(too) simplistically described as a 'successful, invasive clone of our own tissues'. Context has …