Ovarian cancer is the fifth cause of cancer-related death in women and comprises a
histologically and genetically broad range of tumours, including those of epithelial, sex cord …

Despite advances in medicine, ovarian cancer remains the deadliest of the gynecological
malignancies. Herein we present the latest information on the pathophysiology of ovarian …

Ovarian cancer is the most frequent cause of deaths from among gynecologic malignancies.
Due to its asymptomatic development the disease is frequently diagnosed at an advanced …

Multiple genetic alterations play a role in the pathogenesis of ovarian cancer. Although
many key proteins and pathways involved in ovarian carcinogenesis and metastasis have …

The accepted view of ovarian carcinogenesis is that carcinoma begins in the ovary,
undergoes progressive" dedifferentiation" from a well to a poorly differentiated tumor, and …

Prolongation of ovarian epithelial cancer survival depends on early detection or improved
responses to chemotherapy. Gains in either have been modest at best. Understanding the …

Ovarian cancer is a deadly disease for which there is no effective means of early detection.
Ovarian carcinomas comprise a diverse group of neoplasms, exhibiting a wide range of …

Little is known regarding the early aspects of ovarian carcinogenesis. As a consequence,
the identification of women at risk for the disease is based primarily on clinical grounds, with …

Malignant epithelial tumors (carcinomas) are the most common ovarian cancers and also
the most lethal gynecological malignancies. Based on histopathology and molecular genetic …

In an era of promising advances in cancer research, there are considerable and even
alarming gaps in the fundamental knowledge and understanding of ovarian cancer …