Although great success has been achieved in selective C–C bond cleavage via the
intramolecular radical remote migration process of several carbon-based groups, the …

Just as “Deconstructivism” appeared as a novel movement in architecture in the 1980s,
deconstructive approaches have recently emerged as excellent strategies for scaffold …

In recent years, radical C–C bond cleavage reactions have been increasingly understood
and used to perform transformations that complement traditional ionic processes. However …

Skeletal editing is an important strategy in organic synthesis as it modifies the carbon
backbone to tailor molecular structures with precision, enabling access to compounds with …

Radical additions onto olefins have surfaced as an increasingly powerful strategy for the
synthesis of difunctionalized scaffolds. However, despite of major advances, known …

Conspectus Alkenes are ubiquitous in natural products and are extensively used as
synthetic feedstocks in multiple fields including organic synthesis, medicinal chemistry, and …

Activation and cleavage of carbon–carbon (C–C) bonds is a fundamental transformation in
organic chemistry while inert C–C bonds cleavage remains a long-standing challenge …

With a significant prominence in various strain release transformations, the strained
cycloalkanols act as 'n'carbon synthons in a multitude of diversified reactions. Their ease of …

The carbon‐carbon (C—C) σ‐bonds construct the fundamental frameworks of organic
molecules. The direct functionalization of C—C bonds represents one of the most efficient …

Developing strategies enabling the modification of underlying molecular frameworks
facilitates access to underexplored chemical spaces. Skeletal editing is an emerging …