The role of insulin-like growth factor-1 (IGF-1) in growth and reproduction in female brown house snakes (Lamprophis fuliginosus)

AM Sparkman, D Byars, NB Ford… - General and comparative …, 2010 - Elsevier
Insulin-like growth factor-1 (IGF-1) is a peptide hormone critically involved in the regulation
of key life-history traits such as growth and reproduction. Its structure and function are well …

Evolutionary ecology of endocrine‐mediated life‐history variation in the garter snake Thamnophis elegans

AM Sparkman, CM Vleck, AM Bronikowski - Ecology, 2009 - Wiley Online Library
The endocrine system plays an integral role in the regulation of key life‐history traits. Insulin‐
like growth factor‐1 (IGF‐1) is a hormone that promotes growth and reproduction, and it has …

Insulin-like signaling (IIS) responses to temperature, genetic background, and growth variation in garter snakes with divergent life histories

DM Reding, EA Addis, MG Palacios… - General and …, 2016 - Elsevier
The insulin/insulin-like signaling pathway (IIS) has been shown to mediate life history trade-
offs in mammalian model organisms, but the function of this pathway in wild and non …

Evolution and function of the insulin and insulin-like signaling network in ectothermic reptiles: some answers and more questions

TS Schwartz, AM Bronikowski - Integrative and Comparative …, 2016 - academic.oup.com
The insulin and insulin-like signaling (IIS) molecular network regulates cellular growth and
division, and influences organismal metabolism, growth and development, reproduction …

Rates of molecular evolution vary in vertebrates for insulin-like growth factor-1 (IGF-1), a pleiotropic locus that regulates life history traits

AM Sparkman, TS Schwartz, JA Madden… - General and …, 2012 - Elsevier
Insulin-like growth factor-1 (IGF-1) is a member of the vertebrate insulin/insulin-like growth
factor/relaxin gene family necessary for growth, reproduction, and survival at both the …

Nutritional modulation of IGF-1 in relation to growth and body condition in Sceloporus lizards

CA Duncan, AE Jetzt, WS Cohick… - General and Comparative …, 2015 - Elsevier
Nutrition and energy balance are important regulators of growth and the growth
hormone/insulin-like growth factor (GH/IGF) axis. However, our understanding of these …

Testosterone Reduces Growth and Hepatic IGF-1 mRNA in a Female-Larger Lizard, Sceloporus undulatus: Evidence of an Evolutionary Reversal in Growth …

CA Duncan, WS Cohick… - Integrative Organismal …, 2020 - academic.oup.com
Previous research has demonstrated that testosterone (T) can inhibit growth in female-larger
species and stimulate growth in male-larger species, but the underlying mechanisms of this …

Hormones and reproduction in free-ranging snakes

DF DeNardo, EN Taylor - Reproductive biology and phylogeny …, 2011 - api.taylorfrancis.com
Jacobs and Wingfield 2000). Thus, measurements of circulating hormone concentrations are
a vital component of understanding the complexity of the timing of behavioral and …

[HTML][HTML] Insulin-like growth factor 1 of wild vertebrates in a life-history context

J Lodjak, S Verhulst - Molecular and Cellular Endocrinology, 2020 - Elsevier
Broad variation in intra-and interspecific life-history traits is largely shaped by resource
limitation and the ensuing allocation trade-offs that animals are forced to make. Insulin-like …

Gene expression of the IGF hormones and IGF binding proteins across time and tissues in a model reptile

AE Beatty, TS Schwartz - Physiological genomics, 2020 - journals.physiology.org
The insulin and insulin-like signaling (IIS) network regulates cellular processes including pre-
and postnatal growth, cellular development, wound healing, reproduction, and longevity …