Melatonin research has been experiencing hyper growth in the last two decades; this relates
to its numerous physiological functions including anti-inflammation, oncostasis, circadian …

Stem cells have emerged as an important approach to repair and regenerate damaged
tissues or organs and show great therapeutic potential in a variety of diseases. However, the …

Preservation of a robust circadian rhythmicity (particulsarly of the sleep/wake cycle), a
proper nutrition and adequate physical exercise are key elements for healthy aging. Aging …

Biological ageing is generally accompanied by a gradual loss of cellular functions and
physiological integrity of organ systems, the consequential enhancement of vulnerability …

Melatonin is ubiquitous molecule with wide distribution in nature and is produced by many
living organisms. In human beings, pineal gland is the major site for melatonin production …

Neurodegeneration is the hallmark of many chronic progressive neurogical disorders
characterized by specific clinical, morphological and biochemical features. Central nervous …

Neurodegenerative diseases are the second most common cause of death and
characterized by progressive impairments in movement or mental functioning in the central …

Melatonin, an indoleamine hormone produced and secreted at night by pinealocytes and
extra-pineal cells, plays an important role in timing circadian rhythms (24-h internal clock) …

Melatonin is a tryptophan-derived ancestral molecule evolved in bacteria. According to the
endosymbiotic theory, eukaryotic cells received mitochondria, plastids, and other organelles …

Melatonin is a powerful hormone and antioxidant with numerous effects on the metabolism
and the health of humans. Available as a dietary supplement in the United States since …