Rationale: Idiopathic pulmonary fibrosis (IPF) causes considerable global morbidity and
mortality, and its mechanisms of disease progression are poorly understood. Recent …

Rationale: Differences in the lung microbial community influence idiopathic pulmonary
fibrosis (IPF) progression. Whether the lung microbiome influences IPF host defense …

Rationale: Changes in the respiratory microbiome are associated with disease progression
in idiopathic pulmonary fibrosis (IPF). The role of the host response to the respiratory …

Background Idiopathic pulmonary fibrosis (IPF) is the most frequent and severe form of
idiopathic interstitial pneumonias. Although IPF has not been thought to be associated with …

Rationale: Changes in the pulmonary microbiota are associated with progressive respiratory
diseases including chronic obstructive pulmonary disease (COPD). Whether there is a …

Idiopathic pulmonary fibrosis (IPF) is a severe form of lung fibrosis with a high mortality rate.
However, the etiology of IPF remains unknown. Here, we report that alterations in lung …

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrosing interstitial lung
disease that commonly affects older adults and is associated with the histopathological …

Rationale: The “gut–lung axis” is commonly invoked to explain the microbiome's influence
on lung inflammation. Yet the lungs harbor their own microbiome, which is altered in …

The healthy lung was long thought of as sterile, but recent advances using molecular
sequencing approaches have detected bacteria at low levels. Healthy lung bacteria largely …

Acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF) have been defined as events
of clinically significant respiratory deterioration with an unidentifiable cause. They carry a …