Approximately 8% of patients with schizophrenia are diagnosed before age 18, and 18%
experience their first symptoms before age 18. This narrative review explores the …

Childhood onset schizophrenia (COS) is diagnosed before the age of 13 years, and early
onset schizophrenia (EOS) is diagnosed before the age of 18 years. EOS is considered …

Schizophrenia, a neurodevelopmental disorder that most often manifests in late
adolescence or early adulthood, causes significant disturbances in perception, emotion …

Schizophrenia is a neurodevelopmental disorder with a multifactorial etiology. Pediatric
schizophrenia consists of early-onset schizophrenia (onset prior to age 18 years) and …

Background: In the past 10 years, there has been increased research on childhood‐onset
schizophrenia and clear advances have been achieved. Method: This annotation reviews …

Purpose Although first-episode psychosis (FEP) in youth, particularly early-onset
schizophrenia (EOS), is managed similarly to adult-onset schizophrenia, few antipsychotics …

Antipsychotics are efficacious in the treatment of EOS. Given the lack of efficacy differences
between antipsychotics (except for clozapine for treatment-refractory EOS), we propose that …

More recently, clinicians have recognized that attenuated symptoms and significant disability
precede the onset of frank psychosis in the majority of patients. This awareness has led to …

Objective: Childhood-onset schizophrenia (COS) is a rare but severe form of the disorder,
which is often treatment refractory. Short-term studies have indicated a greater differential …

Childhood-onset schizophrenia is a rare variant of adult-onset schizophrenia. Patients with
early-onset schizophrenia typically have a more chronic course of illness, greater cognitive …