The hypothalamus regulates energy homeostasis by integrating environmental and internal
signals to produce behavioral responses to start or stop eating. Many satiation signals are …

Energy balance is controlled by centres of the brain which receive important inputs from the
gastrointestinal tract, liver, pancreas, adipose tissue and skeletal muscle, mediated by many …

Obesity currently represents a major societal and health challenge worldwide. Its prevalence
has reached epidemic proportions and trends continue to rise, reflecting the need for more …

The intestinal microbiota and the expanded endocannabinoid (eCB) system, or
endocannabinoidome (eCBome), have both been implicated in diet-induced obesity and …

Two complex systems are emerging as being deeply involved in the control of energy
metabolism. The intestinal microbiota, with its warehouse of genes, proteins and small …

The endocannabinoid system, with its receptors and ligands, is present in the gut epithelium
and enteroendocrine cells, and is able to modulate brain functions, both indirectly through …

Abstract Originating from Eastern Asia, the plant Cannabis sativa has been used for
centuries as a medicinal treatment. The unwanted psychotropic effects of one of its major …

Interaction between the gut and the brain is essential for energy homeostasis. In obesity, this
homeostasis is disrupted, leading to a positive energy balance and weight gain. Obesity is a …

Introduction Obesity is a major health problem that is associated with many physiological
and mental disorders, such as diabetes, stroke, and depression. Gut microbiota has been …

Various metabolic disorders are associated with changes in inflammatory tone. Among the
latest advances in the metabolism field, the discovery that gut microorganisms have a major …