Chemoresistance in pancreatic ductal adenocarcinoma: Overcoming resistance to therapy
P Bhoopathi, P Mannangatti, SK Das, PB Fisher… - Advances in Cancer …, 2023 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC), a prominent cause of cancer deaths worldwide,
is a highly aggressive cancer most frequently detected at an advanced stage that limits …
is a highly aggressive cancer most frequently detected at an advanced stage that limits …
[HTML][HTML] The challenge of drug resistance in pancreatic ductal adenocarcinoma: a current overview
Pancreatic ductal adenocarcinoma (PDAC) has one of the highest mortality rates among all
cancer types. Its delayed diagnosis precludes curative resection, thus most of the current …
cancer types. Its delayed diagnosis precludes curative resection, thus most of the current …
[HTML][HTML] Therapeutic resistance in pancreatic ductal adenocarcinoma: Current challenges and future opportunities
A Jain, V Bhardwaj - World journal of gastroenterology, 2021 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related
deaths in the United States. Although chemotherapeutic regimens such as gemcitabine+ …
deaths in the United States. Although chemotherapeutic regimens such as gemcitabine+ …
The biological underpinnings of therapeutic resistance in pancreatic cancer
GL Beatty, G Werba, CA Lyssiotis… - Genes & …, 2021 - genesdev.cshlp.org
Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related mortality in
the United States and has only recently achieved a 5-yr survival rate of 10%. This dismal …
the United States and has only recently achieved a 5-yr survival rate of 10%. This dismal …
Mechanisms of drug resistance of pancreatic ductal adenocarcinoma at different levels
J Du, J Gu, J Li - Bioscience Reports, 2020 - portlandpress.com
Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related
death worldwide, and the mortality of patients with PDAC has not significantly decreased …
death worldwide, and the mortality of patients with PDAC has not significantly decreased …
Unveiling the Resistance to Therapies in Pancreatic Ductal Adenocarcinoma
Despite the ongoing advances in interventional strategies (surgery, chemotherapy,
radiotherapy, and immunotherapy) for managing pancreatic ductal adenocarcinoma …
radiotherapy, and immunotherapy) for managing pancreatic ductal adenocarcinoma …
[HTML][HTML] The landscape of pancreatic cancer therapeutic resistance mechanisms
Pancreatic cancer (pancreatic ductal adenocarcinoma, PDA) is infamously moving to the top
of the list as one of the most lethal cancers with an overall 5 year survival rate of 7%. Multiple …
of the list as one of the most lethal cancers with an overall 5 year survival rate of 7%. Multiple …
Drug resistance in pancreatic cancer: New player caught in act
G Capurso, C Sette - EBioMedicine, 2019 - thelancet.com
Most human cancers display high levels of heterogeneity, a feature that often impacts
negatively on the response to treatments. Indeed, while radio and/or chemotherapy initially …
negatively on the response to treatments. Indeed, while radio and/or chemotherapy initially …
Chemoresistance in pancreatic cancer
S Zeng, M Pöttler, B Lan, R Grützmann… - International journal of …, 2019 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC), generally known as pancreatic cancer (PC),
ranks the fourth leading cause of cancer-related deaths in the western world. While the …
ranks the fourth leading cause of cancer-related deaths in the western world. While the …
CYP3A5 contributes to PDAC chemoresistance
H Thomas - Nature Reviews Gastroenterology & Hepatology, 2016 - nature.com
New research sheds light on the mechanisms underlying resistance to chemotherapeutics in
patients with pancreatic ductal adenocarcinoma (PDAC). Increased expression of CYP3A5 …
patients with pancreatic ductal adenocarcinoma (PDAC). Increased expression of CYP3A5 …