Warburg effect is a dominant phenotype of most cancer cells. Here we show that this
phenotype depends on its environment. When cancer cells are under regular culture …

Cancer cells are different from normal cells in their metabolic properties. Normal cells mostly
rely on mitochondrial oxidative phosphorylation to produce energy. In contrast, cancer cells …

Highlights•Tumor cells increase their metabolic rates as well as glucose uptake to maintain
amplified proliferation,•Consequently, tumor cells switch from mitochondrial oxidative …

It has been observed that both cancer tissue cells and normal proliferating cells (NPCs)
have the Warburg effect. Our goal here is to demonstrate that they do this for different …

Described decades ago, the Warburg effect of aerobic glycolysis is a key metabolic hallmark
of cancer, yet its significance remains unclear. In this Essay, we re-examine the Warburg …

Cancer cells rewire their metabolism to promote growth, survival, proliferation, and long-term
maintenance. The common feature of this altered metabolism is the increased glucose …

Reprogramming of energy metabolism is a key hallmark of cancer. Most cancer cells display
a glycolytic phenotype, with increased glucose consumption and glycolysis rates, and …

An old ideology of killing the cancer cells by starving them is the underlying concept of the
Warburg effect. It is the process of aerobic glycolysis exhibited by the cancer cells …

The Warburg effect was first described by Otto Warburg in the 1920s and describes the
preferential conversion of glucose to lactate as opposed to its metabolism through the citric …

Simple Summary Cancer represents unrestricted growth with the removal of conventional
brakes that control growth under normal conditions. This requires novel mechanisms to …