Regulation of gene expression by reactive oxygen
TP Dalton, HG Shertzer, A Puga - Annual review of …, 1999 - annualreviews.org
▪ Abstract Reactive oxygen intermediates are produced in all aerobic organisms during
respiration and exist in the cell in a balance with biochemical antioxidants. Excess reactive …
respiration and exist in the cell in a balance with biochemical antioxidants. Excess reactive …
Oxidative stress and gene regulation
RG Allen, M Tresini - Free Radical Biology and Medicine, 2000 - Elsevier
Reactive oxygen species are produced by all aerobic cells and are widely believed to play a
pivotal role in aging as well as a number of degenerative diseases. The consequences of …
pivotal role in aging as well as a number of degenerative diseases. The consequences of …
Transcriptional responses to oxidative stress: pathological and toxicological implications
Q Ma - Pharmacology & therapeutics, 2010 - Elsevier
The utilization of molecular oxygen as the terminal electron acceptor for energy production
has in many ways shaped the evolution of complex life, physiology, and certain disease …
has in many ways shaped the evolution of complex life, physiology, and certain disease …
The oxidative stress response.
SL Camhi, P Lee, AM Choi - New horizons (Baltimore, Md.), 1995 - europepmc.org
Oxidative stress resulting from toxic effects of reactive oxygen species (ROS) plays an
important role in the pathogenesis of a variety of diseases and important biological …
important role in the pathogenesis of a variety of diseases and important biological …
Antioxidant and redox regulation of gene transcription
CK Sen, L Packer - The FASEB journal, 1996 - Wiley Online Library
Reactive oxygen species (ROS) are implicated in the pathogenesis of a wide variety of
human diseases. Recent evidence suggests that at moderately high concentrations, certain …
human diseases. Recent evidence suggests that at moderately high concentrations, certain …
[HTML][HTML] Regulation of reactive oxygen species generation in cell signaling
YS Bae, H Oh, SG Rhee, Y Do Yoo - Molecules and cells, 2011 - Elsevier
Reactive oxygen species (ROS) including superoxide anion and hydrogen peroxide (H 2 O
2) are thought to be byproducts of aerobic respiration with damaging effects on DNA …
2) are thought to be byproducts of aerobic respiration with damaging effects on DNA …
The role of antioxidants and antioxidant-related enzymes in protective responses to environmentally induced oxidative stress
J Limón-Pacheco, ME Gonsebatt - Mutation Research/Genetic Toxicology …, 2009 - Elsevier
In aerobic organisms, oxygen is essential for efficient energy production but paradoxically,
produces chronic toxic stress in cells. Diverse protective systems must exist to enable …
produces chronic toxic stress in cells. Diverse protective systems must exist to enable …
Free radical biology and medicine: it's a gas, man!
WA Pryor, KN Houk, CS Foote… - American Journal …, 2006 - journals.physiology.org
We review gases that can affect oxidative stress and that themselves may be radicals. We
discuss O2 toxicity, invoking superoxide, hydrogen peroxide, and the hydroxyl radical. We …
discuss O2 toxicity, invoking superoxide, hydrogen peroxide, and the hydroxyl radical. We …
[HTML][HTML] Oxidative stress: molecular perception and transduction of signals triggering antioxidant gene defenses
JG Scandalios - Brazilian journal of medical and biological research, 2005 - SciELO Brasil
Molecular oxygen (O2) is the premier biological electron acceptor that serves vital roles in
fundamental cellular functions. However, with the beneficial properties of O2 comes the …
fundamental cellular functions. However, with the beneficial properties of O2 comes the …
Redox-dependent transcriptional regulation
H Liu, R Colavitti, II Rovira, T Finkel - Circulation research, 2005 - Am Heart Assoc
Reactive oxygen species contribute to the pathogenesis of a number of disparate disorders
including tissue inflammation, heart failure, hypertension, and atherosclerosis. In response …
including tissue inflammation, heart failure, hypertension, and atherosclerosis. In response …