Hearing loss is a severe high unmet need condition affecting more than 1.5 billion people
globally. There are no licensed medicines for the prevention, treatment or restoration of …

Introduction: Hearing loss has a high prevalence, with aging, noise exposure, ototoxic drug
therapies, and genetic mutations being some of the leading causes of hearing loss. Health …

[illus. 1] Regulators have yet to approve any drugs specifically for the treatment of hearing
loss and related disorders--an untapped multibillion-dollar market that might cover more …

There is a huge potential market for the treatment of hearing loss. Drugs are already
available to ameliorate predictable, damaging effects of excessive noise and ototoxic drugs …

With the completion of the sequencing of the human genome, the field of medicine is
undergoing a dramatic and fundamental change. The identification of our genes and the …

Portions of this work were presented in “Medicines discovery for auditory disease: right drug,
right dose, right time, right patient,” Translational Hearing Research Summit: Biological and …

Introduction: Sensorineural hearing loss (HL) is becoming a global phenomenon at an
alarming rate. Nearly 600 million people have been estimated to have significant HL in at …

Hearing loss is a serious condition affecting more than 1.5 billion people globally. Many
affected people benefit from the use of devices, such as hearing aids, but these do not …

Hearing loss is the most common form of sensory impairment in humans and affects more
than 40 million people in the United States alone. No drug-based therapy has been …

Despite over 20 years of effort in academic research centers, start-up companies, and
established pharmaceutical companies, there are no FDA-approved inner ear therapeutics …