BRD4, the most extensively studied member of the BET family, is an epigenetic regulator
that localizes to DNA via binding to acetylated histones and controls the expression of …

Abstract Bromodomain‐containing 4 (BRD4), a member of Bromo and Extra‐Terminal (BET)
family, recognizes acetylated histones and is of importance in transcription, replication, and …

As epigenetic readers of the histone code, BRD4 is the most extensively and thoroughly
studied member of BET family, which plays a critical role in many human diseases including …

BRD4, characterized by two acetyl-lysine binding bromodomains and an extra-terminal (ET)
domain, is a key chromatin organizer that directs gene activation in chromatin through …

Introduction: The bromodomain-containing protein 4 (BRD4), a member of the bromodomain
and extra-terminal (BET) family, functions as an 'epigenetic reader'that binds to acetylated …

The bromodomain acts to recognize acetylated lysine in histones and transcription proteins
and plays a fundamental role in chromatin-based cellular processes including gene …

Abstract Bromodomain‐containing protein 4 (BRD4), as the most studied member of the
bromodomain and extra‐terminal (BET) family, is a chromatin reader protein interpreting …

Bromodomain-containing protein 4 (BRD4), a member of the bromodomain and
extraterminal (BET) family, is considered to be a major driver of cancer cell growth and a …

Bromodomain and extraterminal (BET) proteins bind acetylated lysine residues in histones
and nonhistone proteins via tandem bromodomains and regulate chromatin dynamics …

The bromodomain and extraterminal (BET) protein Brd4 recruits transcriptional regulatory
complexes to acetylated chromatin. While Brd4 is considered to be a general transcriptional …