Evaluating g-ratio weighted changes in the corpus callosum as a function of age and sex

S Berman, KL West, MD Does, JD Yeatman, AA Mezer - Neuroimage, 2018 - Elsevier
Recent years have seen a growing interest in relating MRI measurements to the structural-
biophysical properties of white matter fibers. The fiber g-ratio, defined as the ratio between …

Modeling conduction delays in the corpus callosum using MRI-measured g-ratio

S Berman, S Filo, AA Mezer - Neuroimage, 2019 - Elsevier
Conduction of action potentials along myelinated axons is affected by their structural
features, such as the axonal g-ratio, the ratio between the inner and outer diameters of the …

In vivo histology of the myelin g-ratio with magnetic resonance imaging

N Stikov, JSW Campbell, T Stroh, M Lavelée, S Frey… - Neuroimage, 2015 - Elsevier
The myelin g-ratio, defined as the ratio between the inner and the outer diameter of the
myelin sheath, is a fundamental property of white matter that can be computed from a simple …

A revised model for estimating g-ratio from MRI

KL West, ND Kelm, RP Carson, MD Does - Neuroimage, 2016 - Elsevier
A key measure of white matter health is the g-ratio, which is defined as the ratio between the
inner axon radius and the outer, myelinated, axon radius. Recent methods have been …

[HTML][HTML] Characterizing axonal myelination within the healthy population: a tract-by-tract mapping of effects of age and gender on the fiber g-ratio

M Cercignani, G Giulietti, NG Dowell, M Gabel… - Neurobiology of …, 2017 - Elsevier
The g-ratio, equal to the ratio of the inner-to-outer diameter of a myelinated axon, is
associated with the speed of conduction, and thus reflects axonal function and integrity. It is …

Age‐related estimates of aggregate g‐ratio of white matter structures assessed using quantitative magnetic resonance neuroimaging

M Bouhrara, RW Kim, N Khattar, W Qian… - Human brain …, 2021 - Wiley Online Library
The g‐ratio, defined as the inner‐to‐outer diameter of a myelinated axon, is associated with
the speed of nerve impulse conduction, and represents an index of axonal myelination and …

[HTML][HTML] Quantitative analysis of the myelin g-ratio from electron microscopy images of the macaque corpus callosum

N Stikov, JSW Campbell, T Stroh, M Lavelée, S Frey… - Data in brief, 2015 - Elsevier
We provide a detailed morphometric analysis of eight transmission electron micrographs
(TEMs) obtained from the corpus callosum of one cynomolgus macaque. The raw TEM …

Promise and pitfalls of g-ratio estimation with MRI

JSW Campbell, IR Leppert, S Narayanan, M Boudreau… - Neuroimage, 2018 - Elsevier
The fiber g-ratio is the ratio of the inner to the outer diameter of the myelin sheath of a
myelinated axon. It has a limited dynamic range in healthy white matter, as it is optimized for …

Whole brain g-ratio mapping using myelin water imaging (MWI) and neurite orientation dispersion and density imaging (NODDI)

W Jung, J Lee, HG Shin, Y Nam, H Zhang, SH Oh… - Neuroimage, 2018 - Elsevier
MR g-ratio, which measures the ratio of the aggregate volume of axons to that of fibers in a
voxel, is a potential biomarker for white matter microstructures. In this study, a new approach …

Scan–rescan of axcaliber, macromolecular tissue volume, and g‐ratio in the spinal cord

T Duval, V Smith, N Stikov, EC Klawiter… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose Recent MRI techniques have been introduced that can extract microstructural
information in the white matter, such as the density or macromolecular content. Translating …