Multidrug-resistant Gram-negative bacteria: a product of globalization

PM Hawkey - Journal of Hospital Infection, 2015 - Elsevier
Global trade and mobility of people has increased rapidly over the last 20 years. This has
had profound consequences for the evolution and the movement of antibiotic resistance …

The global spread of healthcare-associated multidrug-resistant bacteria: a perspective from Asia

JS Molton, PA Tambyah, BSP Ang… - Clinical infectious …, 2013 - academic.oup.com
Since antibiotics were first used, each new introduced class has been followed by a global
wave of emergent resistance, largely originating in Europe and North America where they …

[HTML][HTML] The threat of carbapenem-resistant Enterobacteriaceae in Lebanon: an update on the regional and local epidemiology

RI El-Herte, SS Kanj, GM Matar, GF Araj - Journal of infection and public …, 2012 - Elsevier
Bacterial resistance to antimicrobial agents is increasing. Complex resistant mechanisms
have resulted in a wide spectrum of species and strains with multidrug-resistant patterns. In …

New Delhi metallo-β-lactamase and multidrug resistance: a global SOS?

RA Bonomo - Clinical Infectious Diseases, 2011 - academic.oup.com
A case report of a multidrug-resistant (MDR) infection with a strain of Klebsiella pneumoniae
carrying a novel metallo-b-lactamase (MBL), the New Delhi MBL (NDM-1), appears in this …

Emerging issues in gram-negative bacterial resistance: an update for the practicing clinician

S Vasoo, JN Barreto, PK Tosh - Mayo Clinic Proceedings, 2015 - Elsevier
The rapid and global spread of antimicrobial-resistant organisms in recent years has been
unprecedented. Although resistant gram-positive infections have been concerning to …

The current state of multidrug‐resistant gram‐negative bacilli in North America: insights from the Society of Infectious Diseases Pharmacists

AM Nicasio, JL Kuti, DP Nicolau - … : The Journal of Human …, 2008 - Wiley Online Library
Although much of today's media focuses on multidrug‐resistant gram‐positive bacteria such
as methicillin‐resistant Staphylococcus aureus and vancomycin‐resistant Enterococcus …

Global spread of antibiotic resistance: the example of New Delhi metallo-β-lactamase (NDM)-mediated carbapenem resistance

AP Johnson, N Woodford - Journal of medical …, 2013 - microbiologyresearch.org
The rapidity with which new types of antibiotic resistance can disseminate globally following
their initial emergence or recognition is exemplified by the novel carbapenemase New Delhi …

[HTML][HTML] Current epidemiology and growing resistance of gram-negative pathogens

DM Livermore - The Korean journal of internal medicine, 2012 - ncbi.nlm.nih.gov
In the 1980s, Gram-negative pathogens appeared to have been beaten by oxyimino-
cephalosporins, carbapenems, and fluoroquinolones. Yet these pathogens have fought …

Extended spectrum β-lactamases, carbapenemases and mobile genetic elements responsible for antibiotics resistance in Gram-negative bacteria

A El Salabi, TR Walsh, C Chouchani - Critical reviews in …, 2013 - Taylor & Francis
Infectious diseases due to Gram-negative bacteria are a leading cause of morbidity and
mortality worldwide. Antimicrobial agents represent one major therapeutic tools implicated to …

Evolution of antimicrobial resistance among Enterobacteriaceae (focus on extended spectrum β-lactamases and carbapenemases)

JP Lynch III, NM Clark, GG Zhanel - Expert opinion on …, 2013 - Taylor & Francis
Introduction: Bacteria within the family Enterobacteriaceae are important pathogens in
nosocomial and community settings. Over the past two decades, antimicrobial resistance …