The flagellar sigma factor FliA regulates adhesion and invasion of Crohn disease-associated Escherichia coli via a cyclic dimeric GMP-dependent pathway

L Claret, S Miquel, N Vieille, DA Ryjenkov… - Journal of biological …, 2007 - ASBMB
The invasion of intestinal epithelial cells by the Crohn disease-associated adherent-invasive
Escherichia coli (AIEC) strain LF82 depends on surface appendages, such as type 1 pili and …

Regulatory and functional co‐operation of flagella and type 1 pili in adhesive and invasive abilities of AIEC strain LF82 isolated from a patient with Crohn's disease

N Barnich, J Boudeau, L Claret… - Molecular …, 2003 - Wiley Online Library
Genetic determinants that co‐operate with type 1 pili to mediate invasion were sought for in
adherent‐invasive Escherichia coli strain LF82 isolated from a patient with Crohn's disease …

Type 1 pili‐mediated adherence of Escherichia coli strain LF82 isolated from Crohn's disease is involved in bacterial invasion of intestinal epithelial cells

J Boudeau, N Barnich… - Molecular …, 2001 - Wiley Online Library
We previously characterized the invasive ability of Escherichia coli strain LF82, isolated from
an ileal biopsy of a patient with Crohn's disease. In the present study, we performed TnphoA …

Involvement of Lipoprotein NlpI in the Virulence of Adherent Invasive Escherichia coli Strain LF82 Isolated from a Patient with Crohn's Disease

N Barnich, MA Bringer, L Claret… - Infection and …, 2004 - Am Soc Microbiol
Escherichia coli strain LF82 recovered from a chronic lesion of a patient with Crohn's
disease (CD) is able to adhere to and invade cultured intestinal epithelial cells and to …

The Oxidoreductase DsbA Plays a Key Role in the Ability of the Crohn's Disease-Associated Adherent-Invasive Escherichia coli Strain LF82 To Resist Macrophage …

MA Bringer, N Rolhion, AL Glasser… - Journal of …, 2007 - Am Soc Microbiol
Adherent-invasive Escherichia coli (AIEC) isolated from Crohn's disease patients is able to
adhere to and invade intestinal epithelial cells and to replicate in mature phagolysosomes …

N‐acetyllactosamine‐induced retraction of bundle‐forming pili regulates virulence‐associated gene expression in enteropathogenic Escherichia coli

RM Humphries, TP Griener, SL Vogt… - Molecular …, 2010 - Wiley Online Library
Enteropathogenic Escherichia coli (EPEC) are a major cause of infant morbidity and
mortality due to diarrhoea in developing countries. The pathogenesis of EPEC is dependent …

Novel Topology of BfpE, a Cytoplasmic Membrane Protein Required for Type IV Fimbrial Biogenesis in EnteropathogenicEscherichia coli

TE Blank, MS Donnenberg - Journal of bacteriology, 2001 - Am Soc Microbiol
Enteropathogenic Escherichia coli (EPEC) produces the bundle-forming pilus (BFP), a type
IV fimbria that has been implicated in virulence, autoaggregation, and localized adherence …

The Salmonella typhimurium flagellar basal body protein flie is required for flagellin production and to induce a proinflammatory response in epithelial cells∗

KA Reed, ME Hobert, CE Kolenda, KA Sands… - Journal of Biological …, 2002 - ASBMB
During apical colonization by Salmonella typhimurium, intestinal epithelial cells orchestrate
a proinflammatory response that involves secretion of chemoattractants, predominantly …

Stand-alone EAL domain proteins form a distinct subclass of EAL proteins involved in regulation of cell motility and biofilm formation in enterobacteria

Y El Mouali, H Kim, I Ahmad, A Brauner… - Journal of …, 2017 - Am Soc Microbiol
The second messenger cyclic dimeric GMP (c-di-GMP) is almost ubiquitous among bacteria
as are the c-di-GMP turnover proteins, which mediate the transition between motility and …

Point Mutations in FimH Adhesin of Crohn's Disease-Associated Adherent-Invasive Escherichia coli Enhance Intestinal Inflammatory Response

N Dreux, J Denizot, M Martinez-Medina… - PLoS …, 2013 - journals.plos.org
Adherent-invasive Escherichia coli (AIEC) are abnormally predominant on Crohn's disease
(CD) ileal mucosa. AIEC reference strain LF82 adheres to ileal enterocytes via the common …