Simple Summary The molecular progression of prostate cancer is complex and elusive.
Biological research relies heavily on in vitro and in vivo models that can be used to examine …

Simple Summary This review explores in vivo models of prostate cancer currently published
in the literature, with the focus on the prostate cancer mouse models that have recently been …

The pathogenetic basis of prostate cancer remains highly elusive; its clarification could be
facilitated greatly by laboratory and clinical models of the disease. Although the genetically …

Prostate cancer continues to be the second leading cancer related death among men. In
order to more fully develop effective prevention and intervention strategies for this prevalent …

The complex dynamics of the tumor microenvironment and prostate cancer heterogeneity
have confounded efforts to establish suitable preclinical mouse models to represent human …

Simple Summary The incidence of prostate cancer is rising, primarily due to its prevalence
among elderly men, and with increased life expectancy, these numbers are expected to …

Animal models, particularly mouse models, play a central role in the study of the etiology,
prevention, and treatment of human prostate cancer. While tissue culture models are …

A ccording to US cancer statistics, prostate cancer has been the most commonly diagnosed
cancer and the second leading cause of cancer deaths in American men.'To improve the …

Prostate cancer is a major health problem as it continues to be the most frequently
diagnosed cancer in men in the Western world. While improved early detection significantly …

The progression of prostate cancer is a slow and multiple-step process; clinically detectable
prostate cancer normally manifest in aged men, although the lesions may have originated …