The generation of induced pluripotent stem cells (iPSCs) from differentiated mature cells is
one of the most promising technologies in the field of regenerative medicine. The ability to …

The discovery of induced pluripotent stem cells (iPSCs) by Shinya Yamanaka in 2006 was
heralded as a major breakthrough of the decade in stem cell research. The ability to …

The development of the reprogramming technology led to generation of induced Pluripotent
Stem Cells (iPSC) from a variety of somatic cells. Ever since, fast growing knowledge of …

It is extremely rare for a single experiment to be so impactful and timely that it shapes and
forecasts the experiments of the next decade. Here, we review how two such experiments …

The rising prevalence of progressive neurodegenerative diseases coupled with increasing
longevity poses an economic burden at individual and societal levels. There is currently no …

Induced pluripotent stem cells (iPSCs) have become an essential research platform to study
different human diseases once being discovered by Dr. Shinya Yamanaka in 2006. Another …

In order to expand the promise of regenerative medicine using allogeneic induced
pluripotent stem cells (iPSCs), precise and efficient genome editing of human leukocyte …

Conventional primed human embryonic stem cells and induced pluripotent stem cells
(iPSCs) exhibit molecular and biological characteristics distinct from pluripotent stem cells in …

Stem cells are classified into embryonic stem cells and adult stem cells. An evolving
alternative to conventional stem cell therapies is induced pluripotent stem cells (iPSCs) …

Human induced pluripotent stem cell (iPSC) lines are a powerful tool for studying
development and disease, but the considerable phenotypic variation between lines makes it …