Genomic and transcriptomic research in the discovery and application of colorectal cancer circulating markers

AA Ponomaryova, EY Rykova, AI Solovyova… - International Journal of …, 2023 - mdpi.com
Colorectal cancer (CRC) is the most frequently occurring malignancy in the world. However,
the mortality from CRC can be reduced through early diagnostics, selection of the most …

Methylated circulating tumor DNA as a biomarker for colorectal cancer diagnosis, prognosis, and prediction

FJ Nassar, ZS Msheik, RR Nasr, SN Temraz - Clinical Epigenetics, 2021 - Springer
Worldwide, colorectal cancer (CRC) is a deadly disease whose death rate ranks second
among cancers though its incidence ranks third. Early CRC detection is key and is …

Circulating cell-free nucleic acids as biomarkers in colorectal cancer screening and diagnosis

K Toth, BK Bartak, Z Tulassay… - Expert review of molecular …, 2016 - Taylor & Francis
Screening methods for the most frequent diagnosed malignant tumor, colorectal cancer
(CRC), have limitations. Circulating cell-free DNA (cfDNA) analysis came into focus as a …

[HTML][HTML] Recent Technologies towards Diagnostic and Therapeutic Applications of Circulating Nucleic Acids in Colorectal Cancers

J Chung, S Xiao, Y Gao, YH Soung - International Journal of Molecular …, 2024 - mdpi.com
Liquid biopsy has emerged as a promising noninvasive approach for colorectal cancer
(CRC) management. This review focuses on technologies detecting circulating nucleic …

Molecular biomarkers for an early diagnosis, effective treatment and prognosis of colorectal cancer: Current updates

A Mahasneh, F Al-Shaheri, E Jamal - Experimental and molecular …, 2017 - Elsevier
Colorectal cancer (CRC) is the third most prevalent cancer in the world. Globally, it has been
estimated that about 1.4 million new cases of colorectal cancer are diagnosed every year …

Circulating cell-free DNA as a biomarker in the diagnosis and prognosis of colorectal cancer

IBD Oliveira, RDC Hirata - Brazilian Journal of Pharmaceutical …, 2018 - SciELO Brasil
Colorectal cancer (CRC) is a disease without evident clinical symptoms in early stages,
leading to late diagnosis and disease management. Current diagnostic and prognostic tools …

[HTML][HTML] Circulating and stool nucleic acid analysis for colorectal cancer diagnosis

G De Maio, C Rengucci, W Zoli… - World journal of …, 2014 - ncbi.nlm.nih.gov
In recent years, the need to identify molecular markers characterized by high sensitivity and
specificity in detecting and monitoring early and colorectal cancer lesions has increased. Up …

Novel diagnostic biomarkers in colorectal cancer

AL Zygulska, P Pierzchalski - International journal of molecular sciences, 2022 - mdpi.com
Colorectal cancer (CRC) is still a leading cause of cancer death worldwide. Less than half of
cases are diagnosed when the cancer is locally advanced. CRC is a heterogenous disease …

[HTML][HTML] Circulating tumor DNA detection and its application status in gastric cancer: a narrative review

W Chen, H Yan, X Li, K Ge, J Wu - Translational cancer research, 2021 - ncbi.nlm.nih.gov
Circulating tumor DNA (ctDNA) is the small genomic fragment released by tumor cells into
the circulating system, which carries the gene variation features, such as mutation, insertion …

Circulating tumour DNAs and Non-Coding RNAs as liquid biopsies for the management of colorectal cancer patients

A Lampis, M Ghidini, M Ratti, MB Mirchev… - Gastrointestinal …, 2020 - mdpi.com
Circulating tumour DNAs and non-coding RNAs present in body fluids have been under
investigation as tools for cancer diagnosis, disease monitoring, and prognosis for many …