Although characterized by high reactive oxygen species (ROS) generation, cancer cells
maintain redox homeostasis to avoid severe damage (eg, DNA, protein, and plasma …

Cancer has always been a major disease with an unfavorable impact on human health
worldwide. Redox biology has a close and complicated relationship to the initiation and …

Elevated oxidative stress is a representative hallmark of tumor cells. The development of
redox-responsive nanovectors capable of being selectively activated in cancer cells has …

Reactive oxygen species (ROS) constitute a homeostatic rheostat that modulates signal
transduction pathways controlling cell turnover. Most oncogenic pathways activated in …

Significance: The overabundance of reactive oxygen species (ROS) and antioxidants in
cancer cells represents a challenge for therapeutic intervention, while also providing an …

Cancer cells typically display redox imbalance compared with normal cells due to increased
metabolic rate, accumulated mitochondrial dysfunction, elevated cell signaling, and …

Chemotherapy, combined with other treatments, is widely applied in the clinical treatment of
cancer. However, deficiencies inherited from the traditional route of administration limit its …

Pharmaceutical nanotechnology introduces novel strategies in designing smart nanoscale
drug delivery systems (NDDSs) capable of responding to specific conditions. These smart …

Cancer is complicated to treat because of its high propensity for recurrence and metastasis,
and various side effects of conventional cancer treatments. With the development of …

Advances in nanomaterials science contributed in recent years to develop new devices and
systems in the micro and nanoscale for improving the diagnosis and treatment of cancer …