Onlay-graft of 3D printed Kagome-structure PCL scaffold incorporated with rhBMP-2 based on hyaluronic acid hydrogel

JK Ku, KG Lee, MS Ghim, YK Kim, SH Park… - Biomedical …, 2021 - iopscience.iop.org
The onlay-graft, one of the most difficult graft conditions, is used for diverse clinical
conditions, including plastic and dental surgery. The graft should withstand continuous …

Three-dimensional kagome structures in a PCL/HA-based hydrogel scaffold to lead slow BMP-2 release for effective bone regeneration

SH Lee, KG Lee, J Lee, YS Cho, MS Ghim… - Bio-Design and …, 2023 - Springer
Osteoconductive function is remarkably low in bone disease in the absence of bone tissue
surrounding the grafting site, or if the bone tissue is in poor condition. Thus, an effective …

Evaluation of mechanical strength and bone regeneration ability of 3D printed kagome-structure scaffold using rabbit calvarial defect model

SH Lee, KG Lee, JH Hwang, YS Cho, KS Lee… - Materials Science and …, 2019 - Elsevier
In clinical conditions, the reconstructions performed in the complex and three-dimensional
bone defects in the craniomaxillofacial (CMF) area are often limited in facial esthetics and …

A bioactive hydrogel and 3D printed polycaprolactone system for bone tissue engineering

I Hernandez, A Kumar, B Joddar - Gels, 2017 - mdpi.com
In this study, a hybrid system consisting of 3D printed polycaprolactone (PCL) filled with
hydrogel was developed as an application for reconstruction of long bone defects, which are …

Biocompatibility and dimensional stability through the use of 3D‐printed scaffolds made by polycaprolactone and bioglass‐7: An in vitro and in vivo study

HK Lim, IS Song, WC Choi, YJ Choi, E Kim… - … Implant Dentistry and … - Wiley Online Library
Purpose This experiment aimed to observe the differences in biological properties by
producing BGS‐7+ PCL scaffolds with different weight fractions of BGS‐7 through 3D …

Evaluation of new bone formation in critical-sized rat calvarial defect using 3D printed polycaprolactone/tragacanth gum-bioactive glass composite scaffolds

M Janmohammadi, N Doostmohammadi… - International Journal of …, 2024 - Elsevier
Critical-sized bone defects are a major challenge in reconstructive bone surgery and usually
fail to be treated due to limited remaining bone quality and extensive healing time. The …

Three-dimensional printed polylactic acid scaffold integrated with BMP-2 laden hydrogel for precise bone regeneration

M Cha, YZ Jin, JW Park, KM Lee, SH Han… - Biomaterials …, 2021 - spj.science.org
Background Critical bone defects remain challenges for clinicians, which cannot heal
spontaneously and require medical intervention. Following the development of three …

Strategy for enhancing mechanical properties and bone regeneration of 3D polycaprolactone kagome scaffold: Nano hydroxyapatite composite and its exposure

YS Cho, M Quan, NU Kang, HJ Jeong, MW Hong… - European Polymer …, 2020 - Elsevier
Although attempts to improve tissue-engineering scaffolds have been made using
composite materials (synthetic polymers, bioceramics, etc.), research on bone tissue …

In vivo evaluation of 3D printed polycaprolactone composite scaffold and recombinant human bone morphogenetic protein‐2 for vertical bone augmentation with …

YY Chang, SY Lee, HJ Jeong, YS Cho… - … Research Part B …, 2022 - Wiley Online Library
This study evaluated 3D printed polycaprolactone (PCL) composite scaffold and
recombinant human bone morphogenetic protein‐2 (rhBMP‐2), loaded either onto a PCL …

BMP-2 and hMSC dual delivery onto 3D printed PLA-Biogel scaffold for critical-size bone defect regeneration in rabbit tibia

SH Han, M Cha, YZ Jin, KM Lee, JH Lee - Biomedical Materials, 2020 - iopscience.iop.org
Abstract 3D printing technology has various advantages, and the incorporation of bioactive
substances into the 3D printed scaffold provides the biological and architectural …