The cellular function of the menin tumor suppressor protein, product of the MEN1 gene
mutated in familial multiple endocrine neoplasia type 1, has not been defined. We now show …

Menin is the product of the tumor suppressor gene Men1 that is mutated in the inherited
tumor syndrome multiple endocrine neoplasia type 1 (MEN1). Menin has been shown to …

Human hereditary tumor syndromes serve as an ideal model for studying molecular
pathways regulating tumorigenesis. Multiple endocrine neoplasia type 1 (MEN1), a human …

The product of the multiple endocrine neoplasia type 1 (MEN1) tumor suppressor gene,
menin, is an integral component of MLL1/MLL2 histone methyltransferase complexes …

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disease predisposed
by heterozygous germline mutations in the MEN1 tumor suppressor gene. Biallelic loss of …

The MEN1 gene, mutations in which are responsible for multiple endocrine neoplasia type 1
(MEN1), encodes a 610-amino acid protein, denoted menin. The amino acid sequence of …

Recently the multiple endocrine neoplasia type 1 (MEN-1) tumor suppressor gene was
cloned. MEN-1 encodes a nuclear protein, called menin, of hitherto unknown function. In …

Menin is a tumour suppressor protein whose loss or inactivation causes multiple endocrine
neoplasia 1 (MEN1), a hereditary autosomal dominant tumour syndrome that is …

MEN1 is a tumor suppressor gene that is responsible for multiple endocrine neoplasia type
1 (MEN1) and that encodes a 610-amino-acid protein, called menin. While the majority of …

Although there is indirect genetic evidence that MEN1, the gene for multiple endocrine
neoplasia type 1, is a tumor suppressor gene, little is known about the MEN1-encoded …