Papillary thyroid cancer (PTC) is the most common type of cancer among thyroid
malignancies. Tumor‐related methylation of circulating tumor DNA (ctDNA) in plasma could …

Context: Serum DNA methylation markers may potentially be useful in diagnosing thyroid
cancer and monitoring its recurrence. Objective: The objective of the study was to assess the …

Background Changes in global DNA methylation have been suggested to cause genomic
instability leading to increased risk of cancer. The accumulation of epigenetic changes is …

PURPOSE: DNA methylation plays an important role in thyroid oncogenesis. The aim of this
study was to investigate the connection between global and local DNA methylation status …

Background Alteration of DNA methylation of tumor suppressor genes (TSGs) is one of the
most consistent epigenetic changes in human cancers. DNMTs play several important roles …

Purpose While global hypomethylation of DNA has been found in several malignancies,
studies on thyroid tumours have shown controversial results using different techniques. To …

BACKGROUND: Thymoma is an uncommon neoplasm derived from epithelial cells of the
thymus. Few studies have addressed the genetic alterations that occur in the tumourigenesis …

Overexpression of DNA methyltransferases DNMT1, DNMT3a and DNMT3b has been
reported in various cancers. However, physical binding of DNA methyltransferase (DNMT) to …

Aberrant DNA methylation on CpG islands is one of the most consistent epigenetic changes
in human cancers, and the methylation process is catalyzed by DNA methyltransferase …

DNA methylation (5-methylcytosine, 5-mC) is the best characterized epigenetic mark that
has regulatory roles in diverse biological processes. Recent investigation of RNA …