Association of pericardiac adipose tissue with coronary artery disease

M Li, L Qi, Y Li, S Zhang, L Lin, L Zhou… - Frontiers in …, 2021 - frontiersin.org
Background and Aim Coronary artery disease (CAD) poses a worldwide health threat.
Compelling evidence shows that pericardial adipose tissue (PAT), a brown-like adipose …

Identification of key genes and pathways affected in epicardial adipose tissue from patients with coronary artery disease by integrated bioinformatics analysis

L Tan, Q Xu, Q Wang, R Shi, G Zhang - PeerJ, 2020 - peerj.com
Background Coronary artery disease (CAD) is a common disease with high cost and
mortality. Here, we studied the differentially expressed genes (DEGs) between epicardial …

[HTML][HTML] Identification of key genes and mechanisms of epicardial adipose tissue in patients with diabetes through bioinformatic analysis

H Yang, B Xiong, T Xiong, D Wang, W Yu… - Frontiers in …, 2022 - frontiersin.org
Background: In recent years, peri-organ fat has emerged as a diagnostic and therapeutic
target in metabolic diseases, including diabetes mellitus. Here, we performed a …

Exploring the role of epicardial adipose tissue in coronary artery disease from the difference of gene expression

QC Wang, ZY Wang, Q Xu, RB Li, GG Zhang… - Frontiers in …, 2021 - frontiersin.org
Objectives Epicardial adipose tissue (EAT) is closely adjacent to the coronary arteries and
myocardium, its role as an endocrine organ to affect the pathophysiological processes of the …

Inflammatory biomarkers, angiogenesis and lymphangiogenesis in epicardial adipose tissue correlate with coronary artery disease

Y Si, Z Feng, Y Liu, W Fan, W Shan, Y Zhang, F Shi… - Scientific Reports, 2023 - nature.com
In this study, we explored the relationship between inflammatory adipokine levels and
coronary artery disease (CAD). We collected subcutaneous adipose tissues (SAT) …

Single-Nucleus Transcriptomic Atlas of Human Pericoronary Epicardial Adipose Tissue in Normal and Pathological Conditions

X Liu, M Yuan, D Zhao, Q Zeng, W Li, T Li… - … and Vascular Biology, 2024 - Am Heart Assoc
BACKGROUND: Pericoronary epicardial adipose tissue (EAT) is a unique visceral fat depot
that surrounds the adventitia of the coronary arteries without any anatomic barrier. Clinical …

Examining the effects of coronary artery disease-and mitochondrial biogenesis-related genes' and microRNAs' expression levels on metabolic disorders in epicardial …

N Dogan, AS Ozuynuk-Ertugrul, OO Balkanay… - Gene, 2024 - Elsevier
Background and aims Epicardial adipose tissue (EAT) surrounds the heart and coronary
arteries and is important for comprehending the pathogenesis of coronary artery disease …

[HTML][HTML] Human epicardial adipose tissue inflammation correlates with coronary artery disease

W Fan, Y Si, E Xing, Z Feng, Z Ding, Y Liu, C Wei… - Cytokine, 2023 - Elsevier
Background and aims This study investigates the expression of novel adipocytokines and
inflammatory cells infiltration in epicardial adipose tissue (EAT) and subcutaneous adipose …

Unraveling the role of epicardial adipose tissue in coronary artery disease: partners in crime?

G Conceição, D Martins, I M. Miranda… - International Journal of …, 2020 - mdpi.com
The role of epicardial adipose tissue (EAT) in the pathophysiology of coronary artery
disease (CAD) remains unclear. The present systematic review aimed at compiling …

Integrative miRNA and whole-genome analyses of epicardial adipose tissue in patients with coronary atherosclerosis

M Vacca, M Di Eusanio, M Cariello… - Cardiovascular …, 2016 - academic.oup.com
Background Epicardial adipose tissue (EAT) is an atypical fat depot surrounding the heart
with a putative role in the development of atherosclerosis. Methods and results We profiled …