Mathematical modeling has been used to interpret anatomical and physiological data
obtained from metabolic and hemodynamic studies aimed at investigating structure-function …

Biophysically-based computational models provide a tool for integrating and explaining
experimental data, observations, and hypotheses. Computational models of the pulmonary …

The pulmonary airway, arterial, venous and capillary networks are vast complex branching
and converging systems that are mechanically coupled to the surrounding lung tissue. Early …

The understanding or prediction of specific functions of the lung can be made using compact
models that have identifiable parameters and that are custom designed to the problem of …

Computational modelling of the lungs is an active field of study that integrates computational
advances with lung biophysics, biomechanics, physiology and medical imaging to promote …

Computational fluid dynamics (CFD) modeling of the pulmonary vasculature has the
potential to reveal continuum metrics associated with the hemodynamic stress acting on the …

Computational model analysis has been used widely to understand and interpret complexity
of interactions in the pulmonary system. Pulmonary blood transport is a multi-scale …

We have developed a lung-ventilation model by modeling the lung-volume response to
mouth minus pleural driving pressure (by means of first-and second-order differential …

Medical imaging now enables measurement of the lung in vivo at controlled volumes,
prompting the development of increasingly sophisticated models of the geometry of the lung …

The accurate analysis of patient lung structure and morphology in a clinical setting is one of
the significant challenges in pulmonary medicine. In recent years, computational modelling …