Deficiency of CD3gamma, delta, epsilon, and zeta expression in T cells from AML patients
S Chen, X Zha, L Yang, B Li, Z Liye, Y Li - Hematology, 2011 - Taylor & Francis
In order to elucidate the feature of T‐cell receptor (TCR) signal transduction in T‐cells from
acute myeloid leukemia (AML), the expression levels of CD3gamma, delta, epsilon and zeta …
acute myeloid leukemia (AML), the expression levels of CD3gamma, delta, epsilon and zeta …
Gene expression profiling of CD3γ, δ, ϵ, and ζ chains in CD4+ and CD8+ T cells from human umbilical cord blood
S Chen, L Yang, X Lu, B Li, JYH Chan, D Cai, Y Li - Hematology, 2010 - Taylor & Francis
In order to elucidate the feature of T-cell immune status in umbilical cord blood (CB) from
humans, the expression levels of CD3γ, δ, ϵ, and ζ chain genes in CD4+ and CD8+ T cells …
humans, the expression levels of CD3γ, δ, ϵ, and ζ chain genes in CD4+ and CD8+ T cells …
Enhancement of the TCRζ expression, polyclonal expansion, and activation of t cells from patients with acute myeloid leukemia after IL-2, IL-7, and IL-12 induction
L Shi, S Chen, X Zha, Y Xu, L Xu, L Yang, Y Lu… - DNA and cell …, 2015 - liebertpub.com
Defective T cell receptor (TCR) signaling resulting in lower T cell function plays a crucial role
in the pathogenesis of T cell immunodeficiency in leukemia. Previous studies have indicated …
in the pathogenesis of T cell immunodeficiency in leukemia. Previous studies have indicated …
TCR ζ chain expression in T cells from patients with CML
S Chen, L Yang, S Chen, Y Li - Hematology, 2009 - Taylor & Francis
Chronic myeloid leukemia (CML) is a clonal disorder of the stem cells which has impaired
cell-mediated immune response. Such immune dysfunction may be due to reduced …
cell-mediated immune response. Such immune dysfunction may be due to reduced …
Expressive changes of CD4 (+) T cell subset transcription factors in patients with aplastic anemia, myelodysplastic syndrome and acute myeloid leukemia and their …
XM Feng, HZ Xu, JY Zhang, DM Yin… - … shi yan xue ye xue za …, 2014 - europepmc.org
This study was aimed to compare the expressions of specific transcription factors of CD4 (+)
T cell subset (T-bet, GATA-3, RORγt and FoxP3 mRNA) in peripheral blood of patients with …
T cell subset (T-bet, GATA-3, RORγt and FoxP3 mRNA) in peripheral blood of patients with …
Double-negative (CD4-CD8-) T cells from adult T-cell leukemia patients also have poor expression of the T-cell receptor alpha beta/CD3 complex
H Suzushima, N Asou, S Nishimura, K Nishikawa… - 1993 - ashpublications.org
We present four patients with adult T-cell leukemia (ATL) derived from a novel T-cell subset
(CD4-, CD8-[double-negative, DN], T-cell receptor [TCR] alpha beta+). In the ATL cells of …
(CD4-, CD8-[double-negative, DN], T-cell receptor [TCR] alpha beta+). In the ATL cells of …
Aberrant expression of T-cell markers in acute myeloid leukemia
RE Lewis, JM Cruse, CM Sanders, RN Webb… - … and molecular pathology, 2007 - Elsevier
According to WHO, several T-cell immunophenotypic markers may be aberrantly expressed
in acute myeloid leukemia (AML). TdT may be expressed in greater than one-third of cases …
in acute myeloid leukemia (AML). TdT may be expressed in greater than one-third of cases …
[HTML][HTML] Immunophenotype and increased presence of CD4+ CD25+ regulatory T cells in patients with acute lymphoblastic leukemia
CP Wu, X Qing, CY Wu, H Zhu… - Oncology …, 2012 - spandidos-publications.com
Acute lymphoblastic leukemia (ALL), cancer of the white blood cells, is a heterogeneous
disease that mainly occurs due to the malignant cloning of original and naive lymphocytes …
disease that mainly occurs due to the malignant cloning of original and naive lymphocytes …
Upregulated TCRζ enhances interleukin-2 production in T-cells from patients with CML
X Zha, S Chen, L Yang, L Shi, B Li, X Wu, Y Lu… - DNA and cell …, 2012 - liebertpub.com
T-cell immunodeficiency is a common feature in patients with chronic myeloid leukemia
(CML), and deficiency in CD3 levels was detected in T cells from these patients, which may …
(CML), and deficiency in CD3 levels was detected in T cells from these patients, which may …
[HTML][HTML] Altered expression of the TCR signaling related genes CD3 and FcεRIγ in patients with aplastic anemia
B Li, S Liu, Y Niu, S Fang, X Wu, Z Yu, S Chen… - Journal of Hematology & …, 2012 - Springer
Background Aplastic anemia (AA) is characterized by pancytopenia and bone marrow
hypoplasia, which results from immune-mediated hematopoiesis suppression …
hypoplasia, which results from immune-mediated hematopoiesis suppression …