The recognition of a central role for the endothelium in the development of kidney disease or
the development of vascular lesions in patients with established renal dysfunction has led to …

The kidney is comprised of heterogeneous cell populations that function together to perform
a number of tightly controlled, complex and interdependent processes. Renal endothelial …

BACKGROUND:: Patients with chronic kidney disease (CKD) are at high risk for
atherosclerotic cardiovascular disease (ACVD). In addition to the same epidemiological risk …

Circulating endothelial cells are associated with future vascular events in hemodialysis
patients. Background Endothelial dysfunction and injury are thought to have a key role in the …

Endothelial dysfunction, the shift from a healthy endothelium to a damaged pro-coagulative,
pro-inflammatory, and pro-vasoconstrictive phenotype, is an early event in many chronic …

The endothelium is a functional barrier between vessel wall and blood stream. Assuming the
total human vascular and capillary system occupies a surface area of more than 1,000 m2 …

Endothelial dysfunction is characterized by a shift of the actions of the endothelium toward
reduced vasodilation, a proinflammatory state, and prothrombic properties. It is associated …

The endothelium is considered to be the gatekeeper of the vessel wall, maintaining and
regulating vascular integrity. In patients with chronic kidney disease, protective endothelial …

Endothelial cell dysfunction is considered to be an early event which subsequently leads to
vascular wall disorders. Ultrastructural studies indicate that the endothelial cell changes …

The loss of well-regulated endothelial cell functioning is followed by adverse changes in a
variety of physiological systems, such as the expression of adhesion molecules …