Liquid biopsy of methylation biomarkers in cell-free DNA
H Luo, W Wei, Z Ye, J Zheng, R Xu - Trends in molecular medicine, 2021 - cell.com
Liquid biopsies, in particular, analysis of cell-free DNA (cfDNA), have emerged as a
promising noninvasive diagnostic approach in oncology. Abnormal distribution of DNA …
promising noninvasive diagnostic approach in oncology. Abnormal distribution of DNA …
Cell-free DNA methylation profiling analysis—technologies and bioinformatics
J Huang, L Wang - Cancers, 2019 - mdpi.com
Analysis of circulating nucleic acids in bodily fluids, referred to as “liquid biopsies”, is rapidly
gaining prominence. Studies have shown that cell-free DNA (cfDNA) has great potential in …
gaining prominence. Studies have shown that cell-free DNA (cfDNA) has great potential in …
Detection and relevance of epigenetic markers on ctDNA: recent advances and future outlook
E Lianidou - Molecular Oncology, 2021 - Wiley Online Library
Liquid biopsy, a minimally invasive approach, is a highly powerful clinical tool for the real‐
time follow‐up of cancer and overcomes many limitations of tissue biopsies. Epigenetic …
time follow‐up of cancer and overcomes many limitations of tissue biopsies. Epigenetic …
Cell-free DNA-methylation-based methods and applications in oncology
F Galardi, F De Luca, D Romagnoli, C Biagioni… - Biomolecules, 2020 - mdpi.com
Liquid biopsy based on cell-free DNA (cfDNA) enables non-invasive dynamic assessment of
disease status in patients with cancer, both in the early and advanced settings. The analysis …
disease status in patients with cancer, both in the early and advanced settings. The analysis …
[HTML][HTML] Targeted methylation sequencing of plasma cell-free DNA for cancer detection and classification
L Liu, JM Toung, AF Jassowicz, R Vijayaraghavan… - Annals of …, 2018 - Elsevier
Background Targeted methylation sequencing of plasma cell-free DNA (cfDNA) has a
potential to expand liquid biopsies to patients with tumors without detectable oncogenic …
potential to expand liquid biopsies to patients with tumors without detectable oncogenic …
Single-molecule sequencing enables long cell-free DNA detection and direct methylation analysis for cancer patients
Background Analysis of circulating tumor DNA has become increasingly important as a tool
for cancer care. However, the focus of previous studies has been on short fragments of DNA …
for cancer care. However, the focus of previous studies has been on short fragments of DNA …
DNA methylation-based testing in liquid biopsies as detection and prognostic biomarkers for the four major cancer types
Lung, breast, colorectal, and prostate cancers are the most incident worldwide. Optimal
population-based cancer screening methods remain an unmet need, since cancer detection …
population-based cancer screening methods remain an unmet need, since cancer detection …
Diagnostic power of DNA methylation classifiers for early detection of cancer
D Roy, M Tiirikainen - Trends in cancer, 2020 - cell.com
DNA methylation-based epigenetic signatures have become valuable cancer biomarkers.
We highlight the advantages of liquid biopsy based DNA-methylation profiling for …
We highlight the advantages of liquid biopsy based DNA-methylation profiling for …
[HTML][HTML] Methylation analyses in liquid biopsy
D Lissa, AI Robles - Translational lung cancer research, 2016 - ncbi.nlm.nih.gov
Lung cancer is the leading cause of cancer-related deaths worldwide. Recent
implementation of low-dose computed tomography (LDCT) screening is predicted to lead to …
implementation of low-dose computed tomography (LDCT) screening is predicted to lead to …
[HTML][HTML] Blood-based DNA methylation signatures in cancer: A systematic review
Y Li, Z Fan, Y Meng, S Liu, H Zhan - … Acta (BBA)-Molecular Basis of Disease, 2023 - Elsevier
DNA methylation profiles are in dynamic equilibrium via the initiation of methylation,
maintenance of methylation and demethylation, which control gene expression and …
maintenance of methylation and demethylation, which control gene expression and …