Liver cancer (LC) is the most common cause of cancer death in the United States and the
fifth most common globally. The overexpression of nuclear factor E2 related factor 2 (Nrf2) …

Hepatotoxicity caused by the overdose of various medications is a leading cause of drug-
induced liver injury. Overdose of drugs causes hepatocellular necrosis. Nutraceuticals are …

BACKGROUND: One of the potential strategies for preventing cancers is using food-based
natural products to induce cytoprotective enzymes including phase II and antioxidative …

Cancer chemoprevention involves the application of natural or synthetic compounds to
reduce the risk of cancer development. One of the most effective strategies for preventing …

Cancer chemoprevention involves the use of natural or synthetic compounds to reduce the
risk of developing cancer. One of the potential strategies for preventing cancer in the human …

Accumulating epidemiological and clinical evidence shows that chronic inflammation plays
a critical role in neoplastic transformation and progression. Long-term users of selective …

Oxidative stress is caused by an imbalance of reactive oxygen species (ROS)/reactive
nitrogen species (RNS) and the antioxidative stress defense systems in cells. ROS/RNS or …

Internal metabolism and environmental toxicant exposure can be caused to generate
reactive oxygen species in human organelles which lead to oxidative stress. The nuclear …

Oxidative/nitrosative stress is proposed to be a critical factor in various diseases, including
liver pathologies. Antioxidants derived from medicinal plants have been studied extensively …

Oxidative stress plays a major role in acute and chronic liver injury. In hepatocytes, oxidative
stress frequently triggers antioxidant response by activating nuclear erythroid 2‐related …