Hepatocellular carcinoma (HCC) is characteristically hypervascular, and therefore many
antiangiogenic therapies are under clinical investigation. However, their therapeutic …

Hepatocellular carcinoma (HCC) is characterized by hypervascularity, indicating that
angiogenesis plays a vital role in HCC growth and progression. A number of anti-angiogenic …

Hepatocellular carcinoma (HCC) is the fifth most common and the third most deadly
malignant tumor worldwide. Hypoxia and related oxidative stress are heavily involved in the …

Hepatocellular carcinoma is a leading cause of cancer death worldwide in both adult and
pediatric patients. Despite many options, no ideal treatment exists for this highly malignant …

Hepatocellular carcinoma (HCC) is a hypervascular tumor characterized by
neovascularization, which plays an important role in the growth and progression of HCC …

Hypoxia enhances proliferation, angiogenesis, metastasis, chemoresistance, and
radioresistance of hepatocellular carcinoma (HCC); suppresses differentiation and …

Experimental and clinical data indicate that in human hepatocellular carcinoma (HCC) tumor
progression is associated with angiogenesis and that an increase in microvascular density …

Hepatocellular carcinoma (HCC) is a typical hypervascular tumor. Many angiogenic factors
have been studied in HCC, and several anti-angiogenic therapies have been tested in …

Hepatocellular carcinoma (HCC) is a malignancy characterized by neoangiogenesis that is
determined by an augmented production of proangiogenesis factors by tumor and adjacent …

The present study aimed to investigate the therapeutic efficacy of combining vascular
endothelial growth factor (VEGF) receptor blockade using tyrosine kinase inhibitor PTK787 …