Rad51 and Dmc1 have similar tolerance for mismatches in yeast meiosis

J Choi, LL Xue, Y Cao, J Kim, JE Haber - bioRxiv, 2022 - biorxiv.org
In many eukaryotes, including both budding yeast and mammals, repair of double-strand
breaks (DSBs) is carried out by different apparatus in somatic and meiotic cells. In mitotic …

Rad51 and Dmc1 have similar tolerance for mismatches in yeast meiosis

JE Haber, JJ Choi, L Xue, Y Cao, J Kim - BioRxiv - scholarworks.brandeis.edu
In many eukaryotes, including both budding yeast and mammals, repair of double-strand
breaks (DSBs) is carried out by different apparatus in somatic and meiotic cells. In mitotic …

Down-regulation of Rad51 activity during meiosis in yeast prevents competition with Dmc1 for repair of double-strand breaks

Y Liu, WA Gaines, T Callender, V Busygina, A Oke… - PLoS …, 2014 - journals.plos.org
Interhomolog recombination plays a critical role in promoting proper meiotic chromosome
segregation but a mechanistic understanding of this process is far from complete. In …

Red-Hed regulation: recombinase Rad51, though capable of playing the leading role, may be relegated to supporting Dmc1 in budding yeast meiosis

S Sheridan, DK Bishop - Genes & development, 2006 - genesdev.cshlp.org
DNA strand exchange is the central process of homologous recombination. In budding
yeast, this reaction is catalyzed by the recombinases Rad51 and Dmc1. Rad51 is …

Rad51-independent interchromosomal double-strand break repair by gene conversion requires Rad52 but not Rad55, Rad57, or Dmc1

TJ Pohl, JA Nickoloff - Molecular and cellular biology, 2008 - Am Soc Microbiol
Homologous recombination (HR) is critical for DNA double-strand break (DSB) repair and
genome stabilization. In yeast, HR is catalyzed by the Rad51 strand transferase and its …

Hed1 promotes meiotic crossover formation in Saccharomyces cerevisiae

YJ Kong, JH Joo, KP Kim… - Journal of Microbiology …, 2017 - scholarworks.bwise.kr
Homologous recombination occurs between homologous chromosomes and is significantly
involved in programmed double-strand break (DSB) repair. Activation of two recombinases …

Meiotic crossover control by concerted action of Rad51-Dmc1 in homolog template bias and robust homeostatic regulation

JP Lao, V Cloud, CC Huang, J Grubb, D Thacker… - PLoS …, 2013 - journals.plos.org
During meiosis, repair of programmed DNA double-strand breaks (DSBs) by recombination
promotes pairing of homologous chromosomes and their connection by crossovers. Two …

[PDF][PDF] Rad51, the lead in mitotic recombinational DNA repair, plays a supporting role in budding yeast meiosis

DK Bishop - Cell cycle, 2012 - Taylor & Francis
This manuscript has been published online, prior to printing. O nce the issue is complete
and page numbers have been assigned, the citation will change accordingly. not all, meiotic …

The Repair Mechanisms of DNA Double Strand Breaks in Saccharomyces cerevisiae

JJ Choi - 2023 - search.proquest.com
DNA double-strand breaks (DSBs) are the most lethal form of DNA damage that can lead to
the development of cancer and other diseases. In Saccharomyces cerevisiae, several …

Mek1 down regulates Rad51 activity during yeast meiosis by phosphorylation of Hed1

TL Callender, R Laureau, L Wan, X Chen… - PLoS …, 2016 - journals.plos.org
During meiosis, programmed double strand breaks (DSBs) are repaired preferentially
between homologs to generate crossovers that promote proper chromosome segregation at …