The sympathetic nervous system (SNS) is a major regulatory component of the
cardiovascular (CV) system affecting short-and long-term blood pressure regulation in the …

Chronic sympathetic hyperactivity is present in the majority of patients with hypertension,
and contributes to cardiovascular morbidity and mortality through a number of effects. Its role …

Introduction: An imbalance in the Autonomic Nervous System (ANS) is a central
pathophysiologic mechanism in Heart Failure (HF) and has been a principal target of …

Cumulative evidence nowadays supports the dominant role of sympathetic nervous system
(SNS) activation in patients with hypertension, congestive heart failure, and renal …

Evidence assembled in this review indicates that sympathetic nervous system dysfunction is
crucial in the development of heart failure and essential hypertension. This takes the form of …

Sympathetic overactivation plays an important role in promoting a variety of
pathophysiological processes in cardiovascular diseases (CVDs), including ventricular …

A number of cardiovascular disease have been shown to be characterized by a marked
increase in sympathetic drive to the heart and the peripheral circulation. This is the case for …

Highlights•Renal denervation lowers BP in animal but not man.•BAT lowers BP in both
animals and man.•The extent of denervation or activation relates to BP reduction.The …

Conclusive evidence demonstrates that the sympathetic nervous system activation is a
hallmark of congestive heart failure. This has been shown via a variety of biochemical …

Background The renewed interest of investigators and clinicians the role of the sympathetic
nervous system in hypertension and its relevance as a target for non-pharmacological as …