X‐Ray‐Controlled Generation of Peroxynitrite Based on Nanosized LiLuF4:Ce3+ Scintillators and their Applications for Radiosensitization

Z Du, X Zhang, Z Guo, J Xie, X Dong, S Zhu… - Advanced …, 2018 - Wiley Online Library
Abstract Peroxynitrite (ONOO−), the reaction product derived from nitric oxide (NO) and
superoxide (O2−•), is a potent oxidizing and nitrating agent that modulates complex …

On-demand generation of peroxynitrite from an integrated two-dimensional system for enhanced tumor therapy

S Liu, W Li, H Chen, J Zhou, S Dong, P Zang, B Tian… - ACS …, 2022 - ACS Publications
Nanosystem-mediated tumor radiosensitization strategy combining the features of X-ray with
infinite penetration depth and high atomic number elements shows considerable application …

A lanthanide‐complex‐based ratiometric luminescent probe specific for peroxynitrite

C Song, Z Ye, G Wang, J Yuan… - Chemistry–A European …, 2010 - Wiley Online Library
A lanthanide‐complex‐based ratiometric luminescence probe specific for peroxynitrite
(ONOO−), 4′‐(2, 4‐dimethoxyphenyl)‐2, 2′: 6′, 2′′‐terpyridine‐6, 6′′‐diyl] bis …

Low-dose X-ray-stimulated LaGaO3: Sb, Cr near-infrared persistent luminescence nanoparticles for deep-tissue and renewable in vivo bioimaging

BM Liu, R Zou, SQ Lou, YF Gao, L Ma, KL Wong… - Chemical Engineering …, 2021 - Elsevier
X-ray-stimulated near-infrared persistent luminescence nanoparticles (NIR-PLNPs) offer
attractive capabilities for autofluorescence free deep-seated imaging and depth …

Activatable rare earth near-infrared-II fluorescence ratiometric nanoprobes

Z Sun, H Huang, R Zhang, X Yang, H Yang, C Li… - Nano Letters, 2021 - ACS Publications
Rational design of efficient lanthanide-doped down-shifting nanoparticles (DSNPs) has
attracted tremendous attention. However, energy loss was inevitable in the multiple Ln3+ …

Gd3+ complex-modified NaLuF4-based upconversion nanophosphors for trimodality imaging of NIR-to-NIR upconversion luminescence, X-Ray computed …

A Xia, M Chen, Y Gao, D Wu, W Feng, F Li - Biomaterials, 2012 - Elsevier
Multimodality molecular imaging has recently attracted much attention, because it can take
advantage of individual imaging modalities by fusing together information from several …

Tumor-specific nitric oxide generator to amplify peroxynitrite based on highly penetrable nanoparticles for metastasis inhibition and enhanced cancer therapy

M Shi, J Zhang, Y Wang, C Peng, H Hu, M Qiao… - Biomaterials, 2022 - Elsevier
Multiple biological barriers and tumor metastasis severely impede the tumor therapy. To
address these adversities, an acid-activated poly (ethylene glycol)-poly-l-lysine-2, 3 …

A tumor‐specific platform of peroxynitrite triggering ferroptosis of cancer cells

D Huang, H Huang, M Li, J Fan, W Sun… - Advanced Functional …, 2022 - Wiley Online Library
Peroxynitrite (ONOO−) is a potent oxidant and nucleophile participating in a variety of
pathophysiological processes as well as playing a major role in cancer therapy. However …

Radioactive nano-oxygen generator enhance anti-tumor radio-immunotherapy by regulating tumor microenvironment and reducing proliferation

P Pei, W Shen, Y Zhang, Y Zhang, Z Qi, H Zhou, T Liu… - Biomaterials, 2022 - Elsevier
Oxygen (O 2) is the substance irreplaceable of the body's metabolism, which is not only the
primary consumable of life activities, but also provide the input energy for the whole body …

Tailoring silica-based nanoscintillators for peroxynitrite-potentiated nitrosative stress in postoperative radiotherapy of colon cancer

S Liu, W Li, Y Zhang, J Zhou, Y Du, S Dong, B Tian… - Nano …, 2022 - ACS Publications
The development of a manageable reactive nitrogen species-potentiated nitrosative stress
induction system for cancer therapy has remained elusive. Herein, tailored silica-based …