Animal models of Zika virus infection, pathogenesis, and immunity
TE Morrison, MS Diamond - Journal of virology, 2017 - Am Soc Microbiol
Zika virus (ZIKV) is an emerging mosquito-transmitted flavivirus that now causes epidemics
affecting millions of people on multiple continents. The virus has received global attention …
affecting millions of people on multiple continents. The virus has received global attention …
A susceptible mouse model for Zika virus infection
SD Dowall, VA Graham, E Rayner… - PLoS neglected …, 2016 - journals.plos.org
Zika virus (ZIKV) is a mosquito-borne pathogen which has recently spread beyond Africa
and into Pacific and South American regions. Despite first being detected in 1947, very little …
and into Pacific and South American regions. Despite first being detected in 1947, very little …
Characterization of lethal Zika virus infection in AG129 mice
Background Mosquito-borne Zika virus (ZIKV) typically causes a mild and self-limiting illness
known as Zika fever, which often is accompanied by maculopapular rash, headache, and …
known as Zika fever, which often is accompanied by maculopapular rash, headache, and …
Analysis of the T Cell Response to Zika Virus and Identification of a Novel CD8+ T Cell Epitope in Immunocompetent Mice
Zika virus (ZIKV) is an emerging arbovirus of the Flaviviridae family. Although ZIKV infection
is typically mild and self-limiting in healthy adults, infection has been associated with …
is typically mild and self-limiting in healthy adults, infection has been associated with …
A mouse model of Zika virus pathogenesis
The ongoing Zika virus (ZIKV) epidemic and unexpected clinical outcomes, including
Guillain-Barré syndrome and birth defects, has brought an urgent need for animal models …
Guillain-Barré syndrome and birth defects, has brought an urgent need for animal models …
The emergence of Zika virus and its new clinical syndromes
TC Pierson, MS Diamond - Nature, 2018 - nature.com
Zika virus (ZIKV) is a mosquito-transmitted flavivirus that has emerged as a global health
threat because of its potential to generate explosive epidemics and ability to cause …
threat because of its potential to generate explosive epidemics and ability to cause …
Zika virus pathogenesis and tissue tropism
JJ Miner, MS Diamond - Cell host & microbe, 2017 - cell.com
Although Zika virus (ZIKV) was isolated approximately 70 years ago, few experimental
studies had been published prior to 2016. The recent spread of ZIKV to countries in the …
studies had been published prior to 2016. The recent spread of ZIKV to countries in the …
Animal models of Zika virus infection during pregnancy
Zika virus (ZIKV) emerged suddenly in the Americas in 2015 and was associated with a
widespread outbreak of microcephaly and other severe congenital abnormalities in infants …
widespread outbreak of microcephaly and other severe congenital abnormalities in infants …
Development and characterization of recombinant virus generated from a New World Zika virus infectious clone
J Weger-Lucarelli, NK Duggal… - Journal of …, 2017 - Am Soc Microbiol
Zika virus (ZIKV; family Flaviviridae, genus Flavivirus) is a rapidly expanding global
pathogen that has been associated with severe clinical manifestations, including …
pathogen that has been associated with severe clinical manifestations, including …
Characterization of a 2016 clinical isolate of Zika virus in non-human primates
XF Li, HL Dong, XY Huang, YF Qiu, HJ Wang… - …, 2016 - thelancet.com
Animal models are critical to understand disease and to develop countermeasures for the
ongoing epidemics of Zika virus (ZIKV). Here we report a non-human primate model using a …
ongoing epidemics of Zika virus (ZIKV). Here we report a non-human primate model using a …