Developments in diagnosis and treatment of visceral leishmaniasis during the last decade and future prospects

SA Ejazi, N Ali - Expert review of anti-infective therapy, 2013 - Taylor & Francis
Human visceral leishmaniasis (VL) continues to be a life-threatening neglected tropical
disease, with close to 200 million people at risk of infection globally. Epidemics and …

Current diagnosis and treatment of visceral leishmaniasis

S Mondal, P Bhattacharya, N Ali - Expert review of anti-infective …, 2010 - Taylor & Francis
Human visceral leishmaniasis (VL), a potentially fatal disease, is most prevalent in the
Indian subcontinent, East Africa and South America. Definite diagnosis and effective …

Visceral leishmaniasis: advances in treatment

HC Maltezou - Recent Patents on Anti-Infective Drug Discovery, 2008 - ingentaconnect.com
Visceral leishmaniasis continues to be an important public health problem worldwide. This
vector-borne infection affects approximately 500,000 people annually with more than 50,000 …

Visceral leishmaniasis: what are the needs for diagnosis, treatment and control?

F Chappuis, S Sundar, A Hailu, H Ghalib… - Nature reviews …, 2007 - nature.com
Visceral leishmaniasis (VL) is a systemic protozoan disease that is transmitted by
phlebotomine sandflies. Poor and neglected populations in East Africa and the Indian sub …

Road‐map of pre‐clinical treatment for Visceral Leishmaniasis

P Mazire, V Agarwal, A Roy - Drug Development Research, 2022 - Wiley Online Library
Visceral leishmaniasis (VL) or Kala‐azar, is the most lethal form of leishmaniasis, is still
prevalent in many countries where it is endemic. It is a threat to human life caused by …

Visceral leishmaniasis: current status of control, diagnosis, and treatment, and a proposed research and development agenda

PJ Guerin, P Olliaro, S Sundar, M Boelaert… - The Lancet infectious …, 2002 - thelancet.com
Visceral leishmaniasis is common in less developed countries, with an estimated 500 000
new cases each year. Because of the diversity of epidemiological situations, no single …

Treatment options for visceral leishmaniasis

M Den Boer, RN Davidson - Expert review of anti-infective therapy, 2006 - Taylor & Francis
This review summarizes the current developments in therapy for visceral leishmaniasis. With
the recent introduction of new drugs, the main limits in reducing deaths from visceral …

Recent developments and future prospects in the treatment of visceral leishmaniasis

S Sundar, A Singh - Therapeutic advances in infectious …, 2016 - journals.sagepub.com
Limited therapeutic options in visceral leishmaniasis (VL) make the treatment of this
neglected disease very challenging. In addition to this, long treatment duration and toxic …

Treatment of visceral leishmaniasis (kala-azar): a decade of progress and future approaches

HW Murray - International Journal of Infectious Diseases, 2000 - Elsevier
In 1990, there was essentially one treatment regimen in use for visceral leishmaniasis (kala-
azar) around the world: 20 to 28 days of daily injections of pentavalent antimony (Sb) …

Chemotherapeutics of visceral leishmaniasis: present and future developments

S Sundar, A Singh - Parasitology, 2018 - cambridge.org
Treatment of Visceral Leishmaniasis (VL), a neglected tropical disease, is very challenging
with few treatment options. Long duration of treatment and drug toxicity further limit the target …